Recombinant Mouse FLRT2 protein (His tag) is a Mouse Fragment protein, in the 1 to 539 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M G L Q T T K W P G R G A F I L K F W L I I S L G L Y L Q V S K L L A C P S V C R C D R N F V Y C N E R S L T S V P L G I P E G V T V L Y L H N N Q I N N A G F P A E L H N V Q S V H T V Y L Y G N Q L D E F P M N L P K N V R V L H L Q E N N I Q T I S R A A L A Q L L K L E E L H L D D N S I S T V G V E D G A F R E A I S L K L L F L S K N H L S S V P V G L P V D L Q E L R V D E N R I A V I S D M A F Q N L T S L E R L I V D G N L L T N K G I A E G T F S H L T K L K E F S I V R N S L S H P P P D L P G T H L I R L Y L Q D N Q I N H I P L T A F A N L R K L E R L D I S N N Q L R M L T Q G V F D H L S N L K Q L T A R N N P W F C D C S I K W V T E W L K Y I P S S L N V R G F M C Q G P E Q V R G M A V R E L N M N L L S C P T T T P G L P V F T P A P S T V S P T T Q S P T L S V P S P S R G S V P P A P T P S K L P T I P D W D G R E R V T P P I S E R I Q L S I H F V N D T S I Q V S W L S L F T V M A Y K L T W V K M G H S L V G G I V Q E R I V S G E K Q H L S L V N L E P R S T Y R I C L V P L D A F N Y R T V E D T I C S E A T T H A S Y L N N G S N T A S S H E Q T T S H S M G S
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:21350012, PubMed:25374360, PubMed:25728924). May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D (PubMed:21673655). Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members (PubMed:21673655, PubMed:25728924). Plays a role in fibroblast growth factor-mediated signaling cascades (PubMed:16872596). Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis (PubMed:21350012).
Alternative names
Kiaa0405, Flrt2, Leucine-rich repeat transmembrane protein FLRT2, Fibronectin leucine rich transmembrane protein 2
Recommended products
Recombinant Mouse FLRT2 protein (His tag) is a Mouse Fragment protein, in the 1 to 539 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q8BLU0-1
- Animal free
- No
- Species
- Mouse
- Concentration
- Storage buffer
pH: 7.4
Constituents: 100% PBS
Sequence info
Amino acid sequence
- M G L Q T T K W P G R G A F I L K F W L I I S L G L Y L Q V S K L L A C P S V C R C D R N F V Y C N E R S L T S V P L G I P E G V T V L Y L H N N Q I N N A G F P A E L H N V Q S V H T V Y L Y G N Q L D E F P M N L P K N V R V L H L Q E N N I Q T I S R A A L A Q L L K L E E L H L D D N S I S T V G V E D G A F R E A I S L K L L F L S K N H L S S V P V G L P V D L Q E L R V D E N R I A V I S D M A F Q N L T S L E R L I V D G N L L T N K G I A E G T F S H L T K L K E F S I V R N S L S H P P P D L P G T H L I R L Y L Q D N Q I N H I P L T A F A N L R K L E R L D I S N N Q L R M L T Q G V F D H L S N L K Q L T A R N N P W F C D C S I K W V T E W L K Y I P S S L N V R G F M C Q G P E Q V R G M A V R E L N M N L L S C P T T T P G L P V F T P A P S T V S P T T Q S P T L S V P S P S R G S V P P A P T P S K L P T I P D W D G R E R V T P P I S E R I Q L S I H F V N D T S I Q V S W L S L F T V M A Y K L T W V K M G H S L V G G I V Q E R I V S G E K Q H L S L V N L E P R S T Y R I C L V P L D A F N Y R T V E D T I C S E A T T H A S Y L N N G S N T A S S H E Q T T S H S M G S
- Accession
- Q8BLU0
- Protein length
- Fragment
- Predicted molecular weight
- 57.6 kDa
- Amino acids
- 1 to 539
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:21350012, PubMed:25374360, PubMed:25728924). May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D (PubMed:21673655). Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members (PubMed:21673655, PubMed:25728924). Plays a role in fibroblast growth factor-mediated signaling cascades (PubMed:16872596). Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis (PubMed:21350012).
- Post-translational modifications
N-glycosylated.
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
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1 product image
SDS-PAGE - Recombinant Mouse FLRT2 protein (His tag) (ab276972)
SDS-PAGE analysis of ab276972
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