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Recombinant mouse Galectin 2 protein (Active) is a Mouse Full Length protein, in the 1 to 130 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS, MS.

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Images

SDS-PAGE - Recombinant mouse Galectin 2 protein (Active) (AB211311), expandable thumbnail

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, FuncS, MS

Biologically active

Yes

Amino acid sequence

M G S S H H H H H H S S G L V P R G S H M G S M S E K F E V K D L N M K P G M S L K I K G K I H N D V D R F L I N L G Q G K E T L N L H F N P R F D E S T I V C N T S E G G R W G Q E Q R E N H M C F S P G S E V K I T I T F Q D K D F K V T L P D G H Q L T F P N R L G H N Q L H Y L S M G G L Q I S S F K L E

Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Application

FuncS

Reactivity

Reacts

Dilution info

-

Notes

-

Application

MS

Reactivity

Reacts

Dilution info

-

Notes

-

Associated Products

Select an associated product type

2 products for Alternative Product

Target data

Function

This protein binds beta-galactoside. Its physiological function is not yet known.

Alternative names

Recommended products

Recombinant mouse Galectin 2 protein (Active) is a Mouse Full Length protein, in the 1 to 130 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS, MS.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Applications

SDS-PAGE, FuncS, MS

Biological activity

The ED50 for this effect is equal or higher than 20 μg/ml. Measured by its ability to agglutinate Human red blood cells.

Accession
Q9CQW5-1
Animal free

No

Species

Mouse

Concentration
Loading...
Storage buffer

pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

Sequence info

Amino acid sequence

M G S S H H H H H H S S G L V P R G S H M G S M S E K F E V K D L N M K P G M S L K I K G K I H N D V D R F L I N L G Q G K E T L N L H F N P R F D E S T I V C N T S E G G R W G Q E Q R E N H M C F S P G S E V K I T I T F Q D K D F K V T L P D G H Q L T F P N R L G H N Q L H Y L S M G G L Q I S S F K L E

Accession

Q9CQW5

Protein length

Full Length

Predicted molecular weight

17.3 kDa

Amino acids

1 to 130

Nature

Recombinant

Tags

His tag N-Terminus

Specifications

Form

Liquid

Additional notes

ab211311 was purified using conventional chromatography techniques.

General info

Function

This protein binds beta-galactoside. Its physiological function is not yet known.

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

Galectin 2 also known as LGALS2 is a member of the galectin family of beta-galactoside-binding proteins. It has a molecular mass of approximately 14 kDa. Galectin 2 is mainly expressed in the gastrointestinal tract and is found in tissues such as the small intestine colon and stomach. It functions mechanical as a carbohydrate-binding protein that interacts with cell surface glycoproteins and glycolipids influencing cell adhesion and signaling processes.

Biological function summary

Galectins like Galectin 2 play an important role in cell-cell interactions and cellular communication. Although not part of a larger complex Galectin 2 can bind to specific glycans modulating immune responses and inflammation. It can influence leukocyte migration and cytokine secretion contributing to the modulation of the immune system. Galectin 2 also impacts apoptosis and cell proliferation affecting tissue homeostasis and repair.

Pathways

Galectin 2 is involved in the regulation of immune response and inflammation pathways. It interacts with proteins such as integrins and glycoproteins affecting the signaling pathways that regulate immune cell activity. One example is the NF-kB signaling pathway where Galectin 2 can modulate the activation of this pathway influencing inflammation and immune responses. These interactions highlight its role in fine-tuning immune system functions during inflammation.

Associated diseases and disorders

Galectin 2 has been implicated in inflammatory bowel disease (IBD) due to its expression in the gastrointestinal tract and role in inflammation. It is also associated with cardiovascular diseases as it influences inflammation and immune cell activity which are key in the development of atherosclerosis. Proteins like TNF-alpha known for their role in inflammation and immune responses have connections to Galectin 2 through these disease processes. Understanding Galectin 2's influence on these conditions provides insights into potential therapeutic strategies targeting inflammation and immune responses.

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1 product image

  • SDS-PAGE - Recombinant mouse Galectin 2 protein (Active) (ab211311), expandable thumbnail

    SDS-PAGE - Recombinant mouse Galectin 2 protein (Active) (ab211311)

    15% SDS-PAGE analysis of ab211311 (3 μg).

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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