Recombinant mouse Galectin 2 protein (Active) is a Mouse Full Length protein, in the 1 to 130 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS, MS.
>95% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE, FuncS, MS
Yes
M G S S H H H H H H S S G L V P R G S H M G S M S E K F E V K D L N M K P G M S L K I K G K I H N D V D R F L I N L G Q G K E T L N L H F N P R F D E S T I V C N T S E G G R W G Q E Q R E N H M C F S P G S E V K I T I T F Q D K D F K V T L P D G H Q L T F P N R L G H N Q L H Y L S M G G L Q I S S F K L E
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Select an associated product type
This protein binds beta-galactoside. Its physiological function is not yet known.
Galectin-2, Gal-2, Lgals2
Recombinant mouse Galectin 2 protein (Active) is a Mouse Full Length protein, in the 1 to 130 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS, MS.
>95% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE, FuncS, MS
Yes
The ED50 for this effect is equal or higher than 20 μg/ml. Measured by its ability to agglutinate Human red blood cells.
No
Mouse
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
M G S S H H H H H H S S G L V P R G S H M G S M S E K F E V K D L N M K P G M S L K I K G K I H N D V D R F L I N L G Q G K E T L N L H F N P R F D E S T I V C N T S E G G R W G Q E Q R E N H M C F S P G S E V K I T I T F Q D K D F K V T L P D G H Q L T F P N R L G H N Q L H Y L S M G G L Q I S S F K L E
Full Length
17.3 kDa
1 to 130
Recombinant
His tag N-Terminus
Liquid
ab211311 was purified using conventional chromatography techniques.
This protein binds beta-galactoside. Its physiological function is not yet known.
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
This supplementary information is collated from multiple sources and compiled automatically.
Galectin 2 also known as LGALS2 is a member of the galectin family of beta-galactoside-binding proteins. It has a molecular mass of approximately 14 kDa. Galectin 2 is mainly expressed in the gastrointestinal tract and is found in tissues such as the small intestine colon and stomach. It functions mechanical as a carbohydrate-binding protein that interacts with cell surface glycoproteins and glycolipids influencing cell adhesion and signaling processes.
Galectins like Galectin 2 play an important role in cell-cell interactions and cellular communication. Although not part of a larger complex Galectin 2 can bind to specific glycans modulating immune responses and inflammation. It can influence leukocyte migration and cytokine secretion contributing to the modulation of the immune system. Galectin 2 also impacts apoptosis and cell proliferation affecting tissue homeostasis and repair.
Galectin 2 is involved in the regulation of immune response and inflammation pathways. It interacts with proteins such as integrins and glycoproteins affecting the signaling pathways that regulate immune cell activity. One example is the NF-kB signaling pathway where Galectin 2 can modulate the activation of this pathway influencing inflammation and immune responses. These interactions highlight its role in fine-tuning immune system functions during inflammation.
Galectin 2 has been implicated in inflammatory bowel disease (IBD) due to its expression in the gastrointestinal tract and role in inflammation. It is also associated with cardiovascular diseases as it influences inflammation and immune cell activity which are key in the development of atherosclerosis. Proteins like TNF-alpha known for their role in inflammation and immune responses have connections to Galectin 2 through these disease processes. Understanding Galectin 2's influence on these conditions provides insights into potential therapeutic strategies targeting inflammation and immune responses.
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15% SDS-PAGE analysis of ab211311 (3 μg).
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