Recombinant mouse GDNF protein (Animal Free) is a Mouse Full Length protein, in the 78 to 211 aa range, expressed in Escherichia coli, with >=98% purity, <= 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
M S P D K Q A A L P R R E N R N R Q A A A A S P E N S R G K G R R G Q R G K N R G C V L T A I H L N V T D L G L G Y E T K E E L I F R Y C S G S C E S A E T M Y D K I L K N L S R S R R L T S D K V G Q A C C R P V A F D D D L S F L D D N L V Y H I L R K H S A K R C G C I
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
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Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.
Glial cell line-derived neurotrophic factor, mGDNF, Astrocyte-derived trophic factor, ATF, Gdnf
Recombinant mouse GDNF protein (Animal Free) is a Mouse Full Length protein, in the 78 to 211 aa range, expressed in Escherichia coli, with >=98% purity, <= 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
Determined by reducing and Non-reducing SDS-PAGE
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.
Belongs to the TGF-beta family. GDNF subfamily.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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