Recombinant Mouse IL-19 protein
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Mouse IL-19 protein is a Mouse Full Length protein, in the 25 to 176 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
Interleukin-19, IL-19, Il19
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Mouse IL-19 protein (AB269192)
SDS-PAGE analysis of ab269192 at 1ug/lane under (-) non-reducing and (+) reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Lyophilized
Additional notes
nan
General info
Function
Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed : 12370360, PubMed : 27053520). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5 (PubMed : 15557163). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (PubMed : 33684929). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (By similarity).
Sequence similarities
Belongs to the IL-10 family.
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com