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AB207978

Recombinant Mouse IL-19 protein (Animal Free)

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Recombinant Mouse IL-19 protein (Animal Free) is a Mouse Full Length protein, in the 25 to 176 aa range, expressed in Escherichia coli, with >95%, < 0.05 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Interleukin-19, IL-19, Il19

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 0.05 EU/µg

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8CJ70

Animal free

Yes

Carrier free

No

Species

Mouse

Reconstitution

Reconstitute at 0.1 mg/mL in water

Storage buffer

Constituents: 0.87% Sodium chloride, 0.08% Sodium phosphate

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MLRRCLISVDMRLIEKSFHEIKRAMQTKDTFKNVTILSLENLRSIKPGDVCCMTNNLLTFYRDRVFQDHQERSLEVLRRISSIANSFLCVQKSLERCQVHRQCNCSQEATNATRIIHDNYNQLEVSSAALKSLGELNILLAWIDRNHLETPAA","proteinLength":"Full Length","predictedMolecularWeight":"17.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":176,"aminoAcidStart":25,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q8CJ70","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Lyophilized

Additional notes

The purity of ab207978 was determined by reducing and non-reducing SDS-PAGE.

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General info

Function

Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed : 12370360, PubMed : 27053520). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5 (PubMed : 15557163). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (PubMed : 33684929). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (By similarity).

Sequence similarities

Belongs to the IL-10 family.

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Product protocols

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Target data

Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed : 12370360, PubMed : 27053520). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5 (PubMed : 15557163). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (PubMed : 33684929). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (By similarity).
See full target information Il19
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