Recombinant mouse IL-1ra/IL-1F3 protein (Active) (His tag N-Terminus)
- Bioactive
- What is this?
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Recombinant mouse IL-1ra/IL-1F3 protein (Active) (His tag N-Terminus) is a Mouse Fragment protein, in the 27 to 178 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec.
View Alternative Names
Il-1ra, Il1rn, Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor
- FuncS
Supplier Data
Functional Studies - Recombinant mouse IL-1ra/IL-1F3 protein (Active) (His tag N-Terminus) (AB264457)
Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 for this effect is less or equal to 60 ng/ml with Mouse IL-1 alpha.
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant mouse IL-1ra/IL-1F3 protein (Active) (His tag N-Terminus) (AB264457)
SDS-PAGE - Recombinant mouse IL-1ra/IL-1F3 protein (Active) (3 μg ab264457).
Visualized using Coomassie blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
Additional notes
nan
General info
Function
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Sequence similarities
Belongs to the IL-1 family.
Target data
Product promise
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