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AB283480

Recombinant Mouse IL-25 protein

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Recombinant Mouse IL-25 protein is a Mouse Full Length protein, in the 17 to 169 aa range, expressed in HEK 293 cells, with >95%, suitable for SDS-PAGE.

View Alternative Names

Il17e, Il25, Interleukin-25, IL-25, Interleukin-17E, IL-17E

1 Images
SDS-PAGE - Recombinant Mouse IL-25 protein (AB283480)
  • SDS-PAGE

Lab

SDS-PAGE - Recombinant Mouse IL-25 protein (AB283480)

SDS-page analysis of ab283480.

Key facts

Purity

>95% SDS-PAGE

Expression system

HEK 293 cells

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8VHH8

Animal free

Yes

Carrier free

Yes

Species

Mouse

Reconstitution

Reconstitute in PBS

Storage buffer

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"VSLRIQEGCSHLPSCCPSKEQEPPEEWLKWSSASVSPPEPLSHTHHAESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPLGNSVPLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPRVMA","proteinLength":"Full Length","predictedMolecularWeight":"17.53 kDa","actualMolecularWeight":null,"aminoAcidEnd":169,"aminoAcidStart":17,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":null,"tags":[]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
False
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Specifications

Form

Lyophilized

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General info

Function

Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production (PubMed : 11754819, PubMed : 35615348). Promotes and augments T-helper type 2 responses locally or systemically (PubMed : 35615348). Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction (PubMed : 18768888). In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Induces also the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. Inhibits the differentiation of T-helper (Th17) cells via the production of IL4, IL5 and IL13.

Sequence similarities

Belongs to the IL-17 family.

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Product protocols

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Target data

Cytokine produced by various cells such as eosinophils, T-helper type 2 (Th2) cells or epithelial cells that plays a role in internal safety of adaptive immune responses by regulating cytokine production (PubMed : 11754819, PubMed : 35615348). Promotes and augments T-helper type 2 responses locally or systemically (PubMed : 35615348). Exerts its activity via its receptor composed of IL17RA and IL17RB for signal transduction (PubMed : 18768888). In turn, stimulates the JAK2-STAT5A pathway and promotes the secretion of type-2 associated cytokines including IL4, IL9 and IL13. Induces also the release of IL8, and IL6 from eosinophils through the combined activation of MAPK and NF-kappa-B pathways. Inhibits the differentiation of T-helper (Th17) cells via the production of IL4, IL5 and IL13.
See full target information Il25
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Complementary Products

Primary Antibodies

AB272381

Anti-IL-25 antibody [EPR22391-150] - BSA and Azide free (Detector)

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Secondary Antibodies

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Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

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Assay Kits

AB272200

Human IL-25 ELISA Kit

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Sandwich ELISA - Human IL-25 ELISA Kit (AB272200)

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Proteins & Peptides

AB282392

Recombinant human IL-17A protein (Active)

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Product promise

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