Recombinant Mouse IL-4R protein (His tag) is a Mouse Fragment protein, in the 26 to 233 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
I K V L G E P T C F S D Y I R T S T C E W F L D S A V D C S S Q L C L H Y R L M F F E F S E N L T C I P R N S A S T V C V C H M E M N R P V Q S D R Y Q M E L W A E H R Q L W Q G S F S P S G N V K P L A P D N L T L H T N V S D E W L L T W N N L Y P S N N L L Y K D L I S M V N I S R E D N P A E F I V Y N V T Y K E P R L S F P I N I L M S G V Y Y T A R V R V R S Q I L T G T W S E W S P S I T W Y N H F Q L P L I Q R
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
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Target data
Function
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Alternative names
CD124, Il4ra, Il4r, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA
Recommended products
Recombinant Mouse IL-4R protein (His tag) is a Mouse Fragment protein, in the 26 to 233 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- P16382-1
- Animal free
- No
- Species
- Mouse
- Reconstitution
- Reconstitute at 200 µg/mL in water
- Concentration
- Storage buffer
pH: 7.4
Constituents: 95% PBS, 5% Trehalose
Sequence info
Amino acid sequence
- I K V L G E P T C F S D Y I R T S T C E W F L D S A V D C S S Q L C L H Y R L M F F E F S E N L T C I P R N S A S T V C V C H M E M N R P V Q S D R Y Q M E L W A E H R Q L W Q G S F S P S G N V K P L A P D N L T L H T N V S D E W L L T W N N L Y P S N N L L Y K D L I S M V N I S R E D N P A E F I V Y N V T Y K E P R L S F P I N I L M S G V Y Y T A R V R V R S Q I L T G T W S E W S P S I T W Y N H F Q L P L I Q R
- Accession
- P16382
- Protein length
- Fragment
- Predicted molecular weight
- 26.3 kDa
- Amino acids
- 26 to 233
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
- Sequence similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.
- Post-translational modifications
On IL4 binding, phosphorylated on C-terminal tyrosine residues.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Mouse IL-4R protein (His tag) (ab221203)
SDS-PAGE analysis of reduced ab221203 stained overnight with Coomassie Blue.
The reducing protein migrates as 37-45 kDa in SDS-PAGE.
Downloads
Product protocols
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