Recombinant Mouse MSTN Protein
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Recombinant Mouse MSTN Protein is a Mouse Full Length protein, in the 25 to 376 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level.
View Alternative Names
Gdf8, Mstn, Growth/differentiation factor 8, GDF-8, Myostatin
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Mouse MSTN Protein (AB283413)
Mass determination by ESI-TOF. Predicted MW is 40143.85 Da (+/- 10 Da by ESI-TOF). Observed MW is 40145.89 Da.
- HPLC
Supplier Data
HPLC - Recombinant Mouse MSTN Protein (AB283413)
HPLC analysis of ab283413
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse MSTN Protein (AB283413)
SDS-PAGE of ab283413
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Specifications
Form
Lyophilized
General info
Function
Acts specifically as a negative regulator of skeletal muscle growth.
Sequence similarities
Belongs to the TGF-beta family.
Post-translational modifications
Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase (PubMed:14671324).
Target data
Product promise
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