Recombinant Mouse MSTN Protein is a Mouse Full Length protein, in the 25 to 376 aa range, expressed in HEK 293, with >=95% purity and <= 0.005 EU/µg endotoxin level.
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Key facts
- Purity
- >=95% HPLC
- Endotoxin level
- <= 0.005 EU/µg
- Expression system
- HEK 293 cells
- Tags
- Tag free
- Biologically active
- No
Amino acid sequence
N E G S E R E E N V E K E G L C N A C A W R Q N T R Y S R I E A I K I Q I L S K L R L E T A P N I S K D A I R Q L L P R A P P L R E L I D Q Y D V Q R D D S S D G S L E D D D Y H A T T E T I I T M P T E S D F L M Q A D G K P K C C F F K F S S K I Q Y N K V V K A Q L W I Y L R P V K T P T T V F V Q I L R L I K P M K D G T R Y T G I R S L K L D M S P G T G I W Q S I D V K T V L Q N W L K Q P E S N L G I E I K A L D E N G H D L A V T F P G P G E D G L N P F L E V K V T D T P K R S R R D F G L D C D E H S T E S R C C R Y P L T V D F E A F G W D W I I A P K R Y K A N Y C S G E C E F V F L Q K Y P H T H L V H Q A N P R G S A G P C C T P T K M S P I N M L Y F N G K E Q I I Y G K I P A M V V D R C G C S
Target data
Function
Acts specifically as a negative regulator of skeletal muscle growth.
Alternative names
Gdf8, Mstn, Growth/differentiation factor 8, GDF-8, Myostatin
Recommended products
Recombinant Mouse MSTN Protein is a Mouse Full Length protein, in the 25 to 376 aa range, expressed in HEK 293, with >=95% purity and <= 0.005 EU/µg endotoxin level.
Key facts
- Purity
- >=95% HPLC
- Endotoxin level
- <= 0.005 EU/µg
- Expression system
- HEK 293 cells
- Tags
- Tag free
- Biologically active
- No
- Accession
- O08689-1
- Animal free
- No
- Species
- Mouse
- Reconstitution
- Reconstitute in PBS
- Concentration
- Storage buffer
pH: 7.4
Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic
Sequence info
Amino acid sequence
- N E G S E R E E N V E K E G L C N A C A W R Q N T R Y S R I E A I K I Q I L S K L R L E T A P N I S K D A I R Q L L P R A P P L R E L I D Q Y D V Q R D D S S D G S L E D D D Y H A T T E T I I T M P T E S D F L M Q A D G K P K C C F F K F S S K I Q Y N K V V K A Q L W I Y L R P V K T P T T V F V Q I L R L I K P M K D G T R Y T G I R S L K L D M S P G T G I W Q S I D V K T V L Q N W L K Q P E S N L G I E I K A L D E N G H D L A V T F P G P G E D G L N P F L E V K V T D T P K R S R R D F G L D C D E H S T E S R C C R Y P L T V D F E A F G W D W I I A P K R Y K A N Y C S G E C E F V F L Q K Y P H T H L V H Q A N P R G S A G P C C T P T K M S P I N M L Y F N G K E Q I I Y G K I P A M V V D R C G C S
- Accession
- O08689
- Protein length
- Full Length
- Predicted molecular weight
- 43 kDa
- Amino acids
- 25 to 376
- Nature
- Recombinant
Specifications
- Form
- Lyophilized
General info
- Function
Acts specifically as a negative regulator of skeletal muscle growth.
- Sequence similarities
Belongs to the TGF-beta family.
- Post-translational modifications
Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase (PubMed:14671324).
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- Ambient
- Appropriate long-term storage conditions
- Ambient
Product promise
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Full details and terms and conditions can be found here:
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3 product images
Mass Spectrometry - Recombinant Mouse MSTN Protein (ab283413)
Mass determination by ESI-TOF. Predicted MW is 40143.85 Da (+/- 10 Da by ESI-TOF). Observed MW is 40145.89 Da.
SDS-PAGE - Recombinant Mouse MSTN Protein (ab283413)
SDS-PAGE of ab283413
HPLC - Recombinant Mouse MSTN Protein (ab283413)
HPLC analysis of ab283413
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