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AB276819

Recombinant Mouse NEPH2 protein (His tag)

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Recombinant Mouse NEPH2 protein (His tag) is a Mouse Fragment protein, in the 1 to 535 aa range, expressed in HEK 293 cells, with >96%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Kiaa1867, Neph2, Kirrel3, Kin of IRRE-like protein 3, Kin of irregular chiasm-like protein 3, Nephrin-like protein 2, mKirre

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SDS-PAGE - Recombinant Mouse NEPH2 protein (His tag) (AB276819)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Mouse NEPH2 protein (His tag) (AB276819)

SDS-PAGE analysis of ab276819

Key facts

Purity

>96% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Mouse

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

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Complementary Products

Assay Kits

AB313978

Human KIRREL 3 ELISA Kit

Sandwich ELISA - Human KIRREL 3 ELISA Kit (AB313978)

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Primary Antibodies

AB250077

Anti-KIRREL 3 antibody [EPR11631(2)] - BSA and Azide free

RabMAb|Recombinant

Western blot - Anti-KIRREL 3 antibody [EPR11631(2)] - BSA and Azide free (AB250077)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"linker":null,"sequence":"MRPFQLDLLFLCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNIVTFHCSAKANPAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMA","proteinLength":"Fragment","predictedMolecularWeight":"57.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":535,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":null,"tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Form
Lyophilized
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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General info

Function

Synaptic adhesion molecule required for the formation of target-specific synapses (PubMed : 23637329, PubMed : 26575286). Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation (PubMed : 26575286). Required for the coalescence of vomeronasal sensory neuron axons (PubMed : 23637329). May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells (PubMed : 12665856).

Sequence similarities

Belongs to the immunoglobulin superfamily.

Post-translational modifications

Undergoes proteolysis by a metalloprotease and gives rise to a soluble form.

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Product protocols

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Target data

Synaptic adhesion molecule required for the formation of target-specific synapses (PubMed : 23637329, PubMed : 26575286). Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation (PubMed : 26575286). Required for the coalescence of vomeronasal sensory neuron axons (PubMed : 23637329). May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells (PubMed : 12665856).
See full target information Kirrel3
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Product promise

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