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Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Recombinant Mouse Neuropilin 1 protein (His tag) is a Mouse Fragment protein, in the 22 to 856 aa range, expressed in Baculovirus infected insect, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
>90% SDS-PAGE
< 1 EU/µg
Baculovirus infected insect cells
His tag C-Terminus
SDS-PAGE
No
F R S D K C G G T I K I E N P G Y L T S P G Y P H S Y H P S E K C E W L I Q A P E P Y Q R I M I N F N P H F D L E D R D C K Y D Y V E V I D G E N E G G R L W G K F C G K I A P S P V V S S G P F L F I K F V S D Y E T H G A G F S I R Y E I F K R G P E C S Q N Y T A P T G V I K S P G F P E K Y P N S L E C T Y I I F A P K M S E I I L E F E S F D L E Q D S N P P G G M F C R Y D R L E I W D G F P E V G P H I G R Y C G Q K T P G R I R S S S G V L S M V F Y T D S A I A K E G F S A N Y S V L Q S S I S E D F K C M E A L G M E S G E I H S D Q I T A S S Q Y G T N W S V E R S R L N Y P E N G W T P G E D S Y K E W I Q V D L G L L R F V T A V G T Q G A I S K E T K K K Y Y V K T Y R V D I S S N G E D W I S L K E G N K A I I F Q G N T N P T D V V L G V F S K P L I T R F V R I K P V S W E T G I S M R F E V Y G C K I T D Y P C S G M L G M V S G L I S D S Q I T A S N Q A D R N W M P E N I R L V T S R T G W A L P P S P H P Y T N E W L Q V D L G D E K I V R G V I I Q G G K H R E N K V F M R K F K I A Y S N N G S D W K T I M D D S K R K A K S F E G N N N Y D T P E L R T F S P L S T R F I R I Y P E R A T H S G L G L R M E L L G C E V E A P T A G P T T P N G N P V D E C D D D Q A N C H S G T G D D F Q L T G G T T V L A T E K P T I I D S T I Q S E F P T Y G F N C E F G W G S H K T F C H W E H D S H A Q L R W S V L T S K T G P I Q D H T G D G N F I Y S Q A D E N Q K G K V A R L V S P V V Y S Q S S A H C M T F W Y H M S G S H V G T L R V K L R Y Q K P E E Y D Q L V W M V V G H Q G D H W K E G R V L L H K S L K L Y Q V I F E G E I G K G N L G G I A V D D I S I N N H I S Q E D C A K P T D L D K K N T E I K I D E T G S T P G Y E G E G E G D K N I S R K P G N V L K T L D P L E H H H H H H
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins (PubMed:26503042). Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage (By similarity). Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB (By similarity). Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (PubMed:26503042). Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR (By similarity).
Neuropilin-1, A5 protein, Nrp1, Nrp
Recombinant Mouse Neuropilin 1 protein (His tag) is a Mouse Fragment protein, in the 22 to 856 aa range, expressed in Baculovirus infected insect, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Neuropilin-1, A5 protein, Nrp1, Nrp
>90% SDS-PAGE
< 1 EU/µg
Baculovirus infected insect cells
His tag C-Terminus
SDS-PAGE
No
No
Mouse
pH: 7.4
Constituents: 80% PBS, 20% Glycerol (glycerin, glycerine)
F R S D K C G G T I K I E N P G Y L T S P G Y P H S Y H P S E K C E W L I Q A P E P Y Q R I M I N F N P H F D L E D R D C K Y D Y V E V I D G E N E G G R L W G K F C G K I A P S P V V S S G P F L F I K F V S D Y E T H G A G F S I R Y E I F K R G P E C S Q N Y T A P T G V I K S P G F P E K Y P N S L E C T Y I I F A P K M S E I I L E F E S F D L E Q D S N P P G G M F C R Y D R L E I W D G F P E V G P H I G R Y C G Q K T P G R I R S S S G V L S M V F Y T D S A I A K E G F S A N Y S V L Q S S I S E D F K C M E A L G M E S G E I H S D Q I T A S S Q Y G T N W S V E R S R L N Y P E N G W T P G E D S Y K E W I Q V D L G L L R F V T A V G T Q G A I S K E T K K K Y Y V K T Y R V D I S S N G E D W I S L K E G N K A I I F Q G N T N P T D V V L G V F S K P L I T R F V R I K P V S W E T G I S M R F E V Y G C K I T D Y P C S G M L G M V S G L I S D S Q I T A S N Q A D R N W M P E N I R L V T S R T G W A L P P S P H P Y T N E W L Q V D L G D E K I V R G V I I Q G G K H R E N K V F M R K F K I A Y S N N G S D W K T I M D D S K R K A K S F E G N N N Y D T P E L R T F S P L S T R F I R I Y P E R A T H S G L G L R M E L L G C E V E A P T A G P T T P N G N P V D E C D D D Q A N C H S G T G D D F Q L T G G T T V L A T E K P T I I D S T I Q S E F P T Y G F N C E F G W G S H K T F C H W E H D S H A Q L R W S V L T S K T G P I Q D H T G D G N F I Y S Q A D E N Q K G K V A R L V S P V V Y S Q S S A H C M T F W Y H M S G S H V G T L R V K L R Y Q K P E E Y D Q L V W M V V G H Q G D H W K E G R V L L H K S L K L Y Q V I F E G E I G K G N L G G I A V D D I S I N N H I S Q E D C A K P T D L D K K N T E I K I D E T G S T P G Y E G E G E G D K N I S R K P G N V L K T L D P L E H H H H H H
Fragment
94.7 kDa
22 to 856
Recombinant
His tag C-Terminus
Liquid
Affinity purified
Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins (PubMed:26503042). Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage (By similarity). Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB (By similarity). Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (PubMed:26503042). Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR (By similarity).
Belongs to the neuropilin family.
Mitochondrion membrane
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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15% SDS-PAGE analysis of 3 μg ab219287.
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