Recombinant Mouse PAI1 + PLAT protein is a Mouse Full Length protein, expressed in Insect, with >95% purity and suitable for SDS-PAGE.
>95% SDS-PAGE
Insect cells
Tag free
SDS-PAGE
No
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair (By similarity). Involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (PubMed:28722352). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Plat
Mr1, Pai1, Planh1, Planh1, Pai1, Serpine1, Mr1, Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1
Recombinant Mouse PAI1 + PLAT protein is a Mouse Full Length protein, expressed in Insect, with >95% purity and suitable for SDS-PAGE.
>95% SDS-PAGE
Insect cells
Tag free
SDS-PAGE
No
No
Mouse
pH: 7.4
Constituents: 9.52% HEPES, 0.58% Sodium chloride
Liquid
Mouse sc-tPA is reacted with an excess of Mouse PAI1 stable mutant at physiological pH. The resulting 1:1 molar complex is purified from the remaining PAI1 by affinity chromatography with immobilized antibodies to Mouse tPA.
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair (By similarity). Involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (PubMed:28722352). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Belongs to the serpin family.
Dry Ice
-80°C
-80°C
Upon delivery aliquot
Avoid freeze / thaw cycle
Solubility: > 2 mg/mL
Spectrophotometric Data:
ε0.1%=1.5
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
10% SDS-PAGE
Lane 1: Mouse PAI1, Non-reduced
Lane 2: Mouse tPA, Non-reduced
Lane 3: Mouse PAI1 + tPA, Non-reduced
Lane 4: Mouse PAI1 + tPA, Reduced
Lane 5: Mouse PAI1, Reduced
Lane 6: Mouse tPA, Reduced
Lane 7: Prestained standard
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com