Recombinant Mouse PAP protein (His tag) is a Mouse Full Length protein, in the 1 to 381 aa range, expressed in HEK 293, with >98% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >98% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M R A V P L P L S R T A S L S L G F L L L L S L C L D P G Q A K E L K F V T L V F R H G D R G P I E T F P T D P I T E S S W P Q G F G Q L T Q W G M E Q H Y E L G S Y I R K R Y G R F L N D T Y K H D Q I Y I R S T D V D R T L M S A M T N L A A L F P P E G I S I W N P R L L W Q P I P V H T V S L S E D R L L Y L P F R D C P R F E E L K S E T L E S E E F L K R L H P Y K S F L D T L S S L S G F D D Q D L F G I W S K V Y D P L F C E S V H N F T L P S W A T E D A M I K L K E L S E L S L L S L Y G I H K Q K E K S R L Q G G V L V N E I L K N M K L A T Q P Q K Y K K L V M Y S A H D T T V S G L Q M A L D V Y N G V L P P Y A S C H M M E L Y H D K G G H F V E M Y Y R N E T Q N E P Y P L T L P G C T H S C P L E K F A E L L D P V I S Q D W A T E C M A T S S H Q G R N
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity). Isoform 2. In addition to its tyrosine phosphatase activity, also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP. This extracellular adenosine leads to a decrease in chronic pain by activating A1R in nociceptive neurons.
Alternative names
Acpp, Acp3, Prostatic acid phosphatase, 5'-nucleotidase, Acid phosphatase 3, Ecto-5'-nucleotidase, Fluoride-resistant acid phosphatase, Protein tyrosine phosphatase ACP3, Thiamine monophosphatase, 5'-NT, FRAP, TMPase
Recommended products
Recombinant Mouse PAP protein (His tag) is a Mouse Full Length protein, in the 1 to 381 aa range, expressed in HEK 293, with >98% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >98% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q8CE08-1
- Animal free
- No
- Species
- Mouse
- Concentration
- Storage buffer
pH: 7.4
Constituents: 100% PBS
Sequence info
Amino acid sequence
- M R A V P L P L S R T A S L S L G F L L L L S L C L D P G Q A K E L K F V T L V F R H G D R G P I E T F P T D P I T E S S W P Q G F G Q L T Q W G M E Q H Y E L G S Y I R K R Y G R F L N D T Y K H D Q I Y I R S T D V D R T L M S A M T N L A A L F P P E G I S I W N P R L L W Q P I P V H T V S L S E D R L L Y L P F R D C P R F E E L K S E T L E S E E F L K R L H P Y K S F L D T L S S L S G F D D Q D L F G I W S K V Y D P L F C E S V H N F T L P S W A T E D A M I K L K E L S E L S L L S L Y G I H K Q K E K S R L Q G G V L V N E I L K N M K L A T Q P Q K Y K K L V M Y S A H D T T V S G L Q M A L D V Y N G V L P P Y A S C H M M E L Y H D K G G H F V E M Y Y R N E T Q N E P Y P L T L P G C T H S C P L E K F A E L L D P V I S Q D W A T E C M A T S S H Q G R N
- Accession
- Q8CE08
- Protein length
- Full Length
- Predicted molecular weight
- 42 kDa
- Amino acids
- 1 to 381
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity).
- Sequence similarities
Belongs to the histidine acid phosphatase family.
- Subcellular localisation
- Lysosome membrane
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
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1 product image
SDS-PAGE - Recombinant Mouse PAP protein (His tag) (ab276964)
SDS-PAGE analysis of ab276964
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