Recombinant Mouse PLD3 protein is a Mouse Full Length protein, in the 1 to 488 aa range, expressed in Cell free, with >=85% purity and suitable for SDS-PAGE.
Images
Key facts
- Purity
- >=85% SDS-PAGE
- Expression system
- Cell free
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M K P K L M Y Q E L K V P V E E P A G E L P L N E I E A W K A A E K K A R W V L L V L I L A V V G F G A L M T Q L F L W E Y G D L H L F G P N Q R P A P C Y D P C E A V L V E S I P E G L E F P N A T T S N P S T S Q A W L G L L A G A H S S L D I A S F Y W T L T N N D T H T Q E P S A Q Q G E E V L Q Q L Q A L A P R G V K V R I A V S K P N G P L A D L Q S L L Q S G A Q V R M V D M Q K L T H G V L H T K F W V V D Q T H F Y L G S A N M D W R S L T Q V K E L G V V M Y N C S C L A R D L T K I F E A Y W F L G Q A G S S I P S T W P R S F D T R Y N Q E T P M E I C L N G T P A L A Y L A S A P P P L C P S G R T P D L K A L L N V V D S A R S F I Y I A V M N Y L P T M E F S H P R R F W P A I D D G L R R A A Y E R G V K V R L L I S C W G H S D P S M R S F L L S L A A L H D N H T H S D I Q V K L F V V P T D E S Q A R I P Y A R V N H N K Y M V T E R A S Y I G T S N W S G S Y F T E T A G T S L L V T Q N G H G G L R S Q L E A V F L R D W E S P Y S H D L D T S A N S V G N A C R L L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30111894). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (PubMed:30111894). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity).
Alternative names
Sam9, Pld3, 5'-3' exonuclease PLD3, Choline phosphatase 3, Phosphatidylcholine-hydrolyzing phospholipase D3, Phospholipase D3, Schwannoma-associated protein 9, PLD 3, SAM-9
Recommended products
Recombinant Mouse PLD3 protein is a Mouse Full Length protein, in the 1 to 488 aa range, expressed in Cell free, with >=85% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >=85% SDS-PAGE
- Expression system
- Cell free
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- O35405-1
- Animal free
- Yes
- Species
- Mouse
- Concentration
- Storage buffer
pH: 7.4 - 8
Constituents: 6% Trehalose, 0.87% Sodium chloride, 0.24% Tris, 0.05% dodecyl 2-(trimethylazaniumyl)ethyl phosphate
Sequence info
Amino acid sequence
- M K P K L M Y Q E L K V P V E E P A G E L P L N E I E A W K A A E K K A R W V L L V L I L A V V G F G A L M T Q L F L W E Y G D L H L F G P N Q R P A P C Y D P C E A V L V E S I P E G L E F P N A T T S N P S T S Q A W L G L L A G A H S S L D I A S F Y W T L T N N D T H T Q E P S A Q Q G E E V L Q Q L Q A L A P R G V K V R I A V S K P N G P L A D L Q S L L Q S G A Q V R M V D M Q K L T H G V L H T K F W V V D Q T H F Y L G S A N M D W R S L T Q V K E L G V V M Y N C S C L A R D L T K I F E A Y W F L G Q A G S S I P S T W P R S F D T R Y N Q E T P M E I C L N G T P A L A Y L A S A P P P L C P S G R T P D L K A L L N V V D S A R S F I Y I A V M N Y L P T M E F S H P R R F W P A I D D G L R R A A Y E R G V K V R L L I S C W G H S D P S M R S F L L S L A A L H D N H T H S D I Q V K L F V V P T D E S Q A R I P Y A R V N H N K Y M V T E R A S Y I G T S N W S G S Y F T E T A G T S L L V T Q N G H G G L R S Q L E A V F L R D W E S P Y S H D L D T S A N S V G N A C R L L
- Accession
- O35405
- Protein length
- Full Length
- Predicted molecular weight
- 58.2 kDa
- Amino acids
- 1 to 488
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30111894). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (PubMed:30111894). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity).
- Sequence similarities
Belongs to the phospholipase D family.
- Post-translational modifications
N-glycosylated.
- Subcellular localisation
- Lysosome lumen, Early endosome membrane, Late endosome membrane, Endosome membrane
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Mouse PLD3 protein (ab289741)
SDS-PAGE analysis of ab289741
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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