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Recombinant Mouse RANK protein (His tag) is a Mouse Fragment protein, in the 31 to 214 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.

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Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 1 EU/µg
Expression system
HEK 293 cells
Tags
His tag C-Terminus
Applications
SDS-PAGE
Biologically active
No

Amino acid sequence

V T P P C T Q E R H Y E H L G R C C S R C E P G K Y L S S K C T P T S D S V C L P C G P D E Y L D T W N E E D K C L L H K V C D A G K A L V A V D P G N H T A P R R C A C T A G Y H W N S D C E C C R R N T E C A P G F G A Q H P L Q L N K D T V C T P C L L G F F S D V F S S T D K C K P W T N C T L L G K L E A H Q G T T E S D V V C S S S M T L R R P P K E A Q A Y L P S V D H H H H H H

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Associated Products

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2 products for Alternative Product

Target data

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:20483727, PubMed:23478294, PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (PubMed:23478294). Involved in the regulation of interactions between T-cells and dendritic cells (PubMed:9367155).

Alternative names

Recommended products

Recombinant Mouse RANK protein (His tag) is a Mouse Fragment protein, in the 31 to 214 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.

Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 1 EU/µg
Expression system
HEK 293 cells
Applications
SDS-PAGE
Accession
O35305-1
Animal free
No
Species
Mouse
Reconstitution
Reconstitute in water
Concentration
Loading...
Storage buffer

pH: 7.4
Constituents: 100% PBS

Sequence info

Amino acid sequence

V T P P C T Q E R H Y E H L G R C C S R C E P G K Y L S S K C T P T S D S V C L P C G P D E Y L D T W N E E D K C L L H K V C D A G K A L V A V D P G N H T A P R R C A C T A G Y H W N S D C E C C R R N T E C A P G F G A Q H P L Q L N K D T V C T P C L L G F F S D V F S S T D K C K P W T N C T L L G K L E A H Q G T T E S D V V C S S S M T L R R P P K E A Q A Y L P S V D H H H H H H
Accession
O35305
Protein length
Fragment
Predicted molecular weight
21.28 kDa
Amino acids
31 to 214
Nature
Recombinant
Tags
His tag C-Terminus

Specifications

Form
Lyophilized

General info

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:20483727, PubMed:23478294, PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (PubMed:23478294). Involved in the regulation of interactions between T-cells and dendritic cells (PubMed:9367155).

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle

Product promise

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