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AB9916

Recombinant mouse RANTES protein

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(2 Publications)

Recombinant mouse RANTES protein is a Mouse Full Length protein, expressed in Escherichia coli, with >98%, suitable for SDS-PAGE, FuncS.

View Alternative Names

Scya5, Ccl5, C-C motif chemokine 5, MuRantes, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES

Key facts

Purity

>98% SDS-PAGE

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

Active

Accession

P30882

Animal free

No

Carrier free

No

Species

Mouse

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

The biological activity of this product is determined by its ability to chemoattract total human lymphocyte population and total murine T cell population using a concentration range of 1.0-10.0 ng/ml.
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Sequence info

[{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"10 kDa","actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"P30882","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Lyophilized

Additional notes

Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g).

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General info

Function

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.

Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
See full target information Ccl5
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

NPJ Parkinson's disease 11:157 PubMed40483356

2025

EGFR phosphorylates DNAJB1 to suppress α-synuclein aggregation in Parkinson's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Yun-Yu Huang,Sue-Jane Lin,Wei-Yu Chiang,Yuan-Teng Chang,Chan-Chih Yang,Chia-Yu Liao,Ya-Lan Chang,Chin-Hsien Lin,Shu-Chun Teng

PloS one 16:e0259643 PubMed34752478

2021

Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression.

Applications

Unspecified application

Species

Unspecified reactive species

Nina Zemanová,Kateřina Lněničková,Markéta Vavrečková,Eva Anzenbacherová,Pavel Anzenbacher,Iveta Zapletalová,Petra Hermanová,Tomáš Hudcovic,Hana Kozáková,Lenka Jourová
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com