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AB226312

Recombinant Mouse REG1 protein (His tag)

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Recombinant Mouse REG1 protein (His tag) is a Mouse Full Length protein, in the 22 to 165 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

View Alternative Names

Lithostathine-1, Islet of Langerhans regenerating protein 1, Pancreatic stone protein 1, Pancreatic thread protein 1, Regenerating protein 1, REG 1, PSP, PTP, Reg1

1 Images
SDS-PAGE - Recombinant Mouse REG1 protein (His tag) (AB226312)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Mouse REG1 protein (His tag) (AB226312)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab226312 with 5% enrichment gel and 15% separation gel.

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

6x His tag N-Terminus SUMO tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P43137

Animal free

No

Carrier free

No

Species

Mouse

Storage buffer

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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Complementary Products

Proteins & Peptides

AB225652

Recombinant Human GCKR protein (Tagged)

SDS-PAGE - Recombinant Human GCKR protein (Tagged) (AB225652)

  • 0
  • 0
Proteins & Peptides

AB151338

Recombinant Human EpCAM protein

  • 0
  • 0
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB47099

Anti-REG1 alpha antibody

Western blot - Anti-REG1 alpha antibody (AB47099)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"QEAEEDLPSARISCPEGSNAYSSYCYYFTEDRLTWADADLFCQNMNSGYLVSVLSQAEGNFVASLIKESGTTDANVWTGLHDPKRNRRWHWSSGSLFLYKSWATGSPNSSNRGYCVSLTSNTGYKKWKDDNCDAQYSFVCKFKG","proteinLength":"Full Length","predictedMolecularWeight":"32.2 kDa","actualMolecularWeight":null,"aminoAcidEnd":165,"aminoAcidStart":22,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P43137","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"SUMO","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Regenerating Gene 1 (REG1) also known as Reg1 or pancreatitis-associated protein 1 (PAP1) is a small protein with a molecular mass of approximately 16 kDa. It functions as a C-type lectin and binds carbohydrates affecting diverse biological activities.
Biological function summary

REG1 interacts with numerous cellular processes including cell proliferation survival and differentiation. It is not part of a complex but it displays localization primarily in the pancreas influencing exocrine pancreatic secretion. It also appears in other tissues such as the small intestine. Important in tissue regeneration and protection REG1 helps in repairing damage especially in the context of injury or stress.

Pathways

REG1 influences cell growth and apoptosis regulation. It participates in pathways involving pancreatic acinar cell growth like those modulated by cytokines and inflammatory mediators. REG1 interacts with proteins such as REG3 and they both play essential roles in maintaining cellular homeostasis upon injury particularly in digestive organs.

REG1 has associations with pancreatic inflammations like chronic pancreatitis and diabetes mellitus. Its expression becomes altered in these conditions which suggests a role in pathological processes. Interaction of REG1 with inflammatory cytokines links this protein to disease pathogenesis especially with proteins like IL-6 in the context of chronic inflammation and metabolic dysregulation.
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Specifications

Form

Liquid

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General info

Function

Might act as an inhibitor of spontaneous calcium carbonate precipitation.

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Product protocols

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Target data

Might act as an inhibitor of spontaneous calcium carbonate precipitation.
See full target information Reg1
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Product promise

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