Recombinant Mouse RELM Gamma protein is a Mouse Full Length protein, in the 24 to 111 aa range, expressed in Escherichia coli, with >95% purity, <= 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Images
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- <= 1 EU/µg
- Expression system
- Escherichia coli
- Tags
- Tag free
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M E G T L E S I V E K K V K E L L A N R D D C P S T V T K T F S C T S I T A S G R L A S C P S G M T V T G C A C G Y G C G S W D I R D G N T C H C Q C S T M D W A T A R C C Q L A
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Probable hormone (Probable). Promotes chemotaxis in myeloid cells (PubMed:15064728).
Alternative names
Xcp1, Retnlg, Resistin-like gamma, Resistin-like molecule gamma, Ten-cysteine protein 1, RELMgamma, XCP1
Recommended products
Recombinant Mouse RELM Gamma protein is a Mouse Full Length protein, in the 24 to 111 aa range, expressed in Escherichia coli, with >95% purity, <= 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- <= 1 EU/µg
- Expression system
- Escherichia coli
- Tags
- Tag free
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q8K426-1
- Animal free
- No
- Species
- Mouse
- Reconstitution
- Reconstitute at 0.1 mg/mL in water
- Concentration
- Storage buffer
Constituents: 0.16% Sodium phosphate
Sequence info
Amino acid sequence
- M E G T L E S I V E K K V K E L L A N R D D C P S T V T K T F S C T S I T A S G R L A S C P S G M T V T G C A C G Y G C G S W D I R D G N T C H C Q C S T M D W A T A R C C Q L A
- Accession
- Q8K426
- Protein length
- Full Length
- Predicted molecular weight
- 18.9 kDa
- Amino acids
- 24 to 111
- Nature
- Recombinant
Specifications
- Form
- Lyophilized
- Additional notes
Purity determined by reducing and non-reducing SDS-PAGE.
General info
- Function
Probable hormone (Probable). Promotes chemotaxis in myeloid cells (PubMed:15064728).
- Sequence similarities
Belongs to the resistin/FIZZ family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Resistin-like molecule gamma (RELM Gamma) also known as RETNLG is a small protein with a molecular mass of approximately 12 kDa. RELM Gamma plays a role in innate immune responses and belongs to the resistin-like molecule family. This protein expresses primarily in the gastrointestinal tract lungs and spleen. Mechanically it functions by modulating inflammation and host-pathogen interactions possibly through the alteration of signaling pathways associated with immune responses.
- Biological function summary
RELM Gamma affects several immune system processes. It binds to pattern recognition receptors and influences cytokine secretion which regulates inflammation. RELM Gamma does not form part of a larger protein complex. Its expression often increases in response to microbial infections demonstrating its role in defensive immune mechanisms. Additionally it may modulate the activity of immune cells like macrophages and dendritic cells.
- Pathways
RELM Gamma contributes to inflammatory and immune response pathways. It interacts with pathways such as the Toll-like receptor (TLR) signaling pathway and may influence the Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-kB) pathway. RELM Gamma also has relationships with proteins like interleukin 10 (IL-10) and tumor necrosis factor-alpha (TNF-alpha) that play roles in these pathways.
- Associated diseases and disorders
RELM Gamma associates with conditions like asthma and inflammatory bowel disease (IBD). In asthma altered expression of RELM Gamma affects airway inflammation. For IBD RELM Gamma may contribute to intestinal inflammation along with proteins such as interleukin 6 (IL-6). Understanding its role in these diseases can aid in developing targeted therapies aimed at regulating its function.
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Mouse RELM Gamma protein (ab219132)
4-20% Tris Glycine gel electrophoresis of 1 μg ab219132, followed by Coomassie Blue staining.
Lane 1: Non-reducing conditions.
Lane 2: Reducing conditions.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com