Recombinant Mycobacterium tuberculosis MPT64 protein (His tag)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

MPT64 interacts with the host's immune cell processes impacting the ability of Mycobacterium tuberculosis to survive and persist in the host. MPT64 is part of a larger complex of secreted proteins that modulate the host's immune response aiding in the pathogen's evasion of immune detection. Through these mechanisms MPT64 contributes to the pathogen's virulence. The protein's activity is important in maintaining the infectious cycle by interfering with host defenses and sustaining bacterial growth and spread.

Pathways

MPT64's role in disrupting host immune pathways is significant for tuberculosis progression. It interacts primarily with host signaling pathways linked to the immune response. Although not many pathways are thoroughly mapped for MPT64 its interaction with proteins involved in the regulation of antigen processing and presentation is evident. Such interactions can affect how the immune system recognizes and eliminates Mycobacterium tuberculosis highlighting MPT64's role in immune evasion.