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Recombinant pig Tissue Plasminogen Activator protein is a Pig Full Length protein, expressed in Insect, with >95% purity and suitable for SDS-PAGE, ELISA, WB, FuncS.
Alternative names=Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, PLAT
- Purity
>95% SDS-PAGE
- Expression system
Insect cells
- Tags
Tag free
- Applications
SDS-PAGE, ELISA, WB, FuncS
- Biologically active
Yes
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant pig Tissue Plasminogen Activator protein is a Pig Full Length protein, expressed in Insect, with >95% purity and suitable for SDS-PAGE, ELISA, WB, FuncS.
Alternative names=Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, PLAT
Key facts
- Purity
>95% SDS-PAGE
- Expression system
Insect cells
- Tags
Tag free
- Applications
SDS-PAGE, ELISA, WB, FuncS
- Biologically active
Yes
- Biological activity
>95 percent active
- Accession
- Q8SQ23-1
- Protein length
Full Length
- Animal free
No
- Carrier free
Yes
- Nature
Recombinant
- Species
Pig
- Concentration
- Storage buffer
pH: 7.4
Constituents: 9.52% HEPES, 0.58% Sodium chloride
Specifications
- Form
Liquid
- Additional notes
Sterile filtered through 0.2 micron filter.>95% single chain.
General info
- Function
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy.
- Sequence similarities
Belongs to the peptidase S1 family.
- Post-translational modifications
The single chain, almost fully active enzyme, can be further processed into a two-chain fully active form by a cleavage after Arg-310 catalyzed by plasmin, tissue kallikrein or factor Xa.
Storage
- Shipped at conditions
Dry Ice
- Appropriate long-term storage conditions
-80°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Notes
Produced using non-baculovirus insect cells.
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