Recombinant rat CERK protein (Active)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

CERK plays a vital role in maintaining the balance of lipid signaling molecules within cells. It acts as an important mediator in the conversion process that produces C1P a molecule involved in signaling pathways that regulate cell survival proliferation and inflammatory responses. While not part of a larger protein complex CERK often interacts with other signaling lipids and proteins to execute its biological functions effectively.

Pathways

CERK is an important component of the ceramide signaling pathway and the sphingolipid metabolism pathway. Within these pathways CERK works alongside sphingosine kinase and other enzymes to regulate the balance of sphingolipids which are critical for cell signaling and membrane structure. The signaling pathway involving CERK influences cellular responses by altering lipid signaling molecules affecting cellular dynamics including apoptosis and growth processes.