Recombinant Rat HSC70 Interacting Protein HIP is a Rat Full Length protein, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, WB.
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Fam10a1, Hip, Hsc70-interacting protein, Protein FAM10A1, Protein ST13 homolog
Recombinant Rat HSC70 Interacting Protein HIP is a Rat Full Length protein, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, WB.
Constituents: 0.418% MOPS, 0.375% Potassium chloride, 0.019% Magnesium chloride
Purification by Multi step chromatography.
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Belongs to the FAM10 family.
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