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Recombinant rat IL-15 protein is a Rat Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS.

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Key facts

Purity
>95% SDS-PAGE
Expression system
Escherichia coli
Tags
Tag free
Applications
SDS-PAGE, FuncS
Biologically active
Yes

Amino acid sequence

M N W I D V R Y D L E K I E S L I Q F I H I D T T L Y T D S D F H P S C K V T A M N C F L L E L Q V I L H E Y S N M T L N E T V R N V L Y L A N S T L S S N K N V I E S G C K E C E E L E E R N F T E F L Q S F I H I V Q M F I N T S

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
FuncS
Reactivity
Reacts
Dilution info
-
Notes

-

Associated Products

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Target data

Function

Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity).

Alternative names

Interleukin-15, IL-15, Il15

Recommended products

Recombinant rat IL-15 protein is a Rat Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS.

Key facts

Purity
>95% SDS-PAGE
Expression system
Escherichia coli
Applications
SDS-PAGE, FuncS
Biological activity
The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Accession
P97604
Animal free
No
Species
Rat
Reconstitution
Reconstitute in 50 mM Tris, pH 8.5
Concentration
Loading...

Sequence info

Amino acid sequence

M N W I D V R Y D L E K I E S L I Q F I H I D T T L Y T D S D F H P S C K V T A M N C F L L E L Q V I L H E Y S N M T L N E T V R N V L Y L A N S T L S S N K N V I E S G C K E C E E L E E R N F T E F L Q S F I H I V Q M F I N T S
Accession
P97604
Protein length
Full Length
Nature
Recombinant

Specifications

Form
Lyophilized
Additional notes

Greater than 96% by SDS-PAGE and HPLC analyses.

General info

Function

Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity).

Sequence similarities

Belongs to the IL-15/IL-21 family.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

This product is an active protein and may elicit a biological response in vivo, handle with caution.

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