Recombinant rat PAI1 protein (Biotin) is a Rat Full Length protein, in the 24 to 402 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS.
>95% SDS-PAGE
Escherichia coli
Tag free
SDS-PAGE, FuncS
Yes
Biotin
S P L P E S H T A Q Q A T N F G V K V F Q H V V Q A S K D R N V V F S P Y G V S S V L A M L Q L T T A G K T R Q Q I Q D A M G F N I S E R G T A P A L R K L S K E L M G S W N K N E I S T A D A I F V Q R D L E L V Q G F M P H F F K L F R T T V K Q V D F S E V E R A R F I I N D W V E R H T K G M I S D L L A K G A V N E L T R L V L V N A L Y F N G Q W K T P F L E A S T H Q R L F H K S D G S T I S V P M M A Q N N K F N Y T E F T T P D G H E Y D I L E L P Y H G E T L S M F I A A P F E K D V P L S A I T N I L D A E L I R Q W K S N M T R L P R L L I L P K F S L E T E V D L R G P L E K L G M T D I F S S T Q A D F T S L S D Q E Q L S V A Q A L Q K V K I E V N E S G T V A S S S T A I L V S A R M A P T E M V L D R S F L F V V R H N P T E T I L F M G Q L M E P
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Select an associated product type
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Pai1, Planh1, Serpine1, Pai1, Planh1, Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1
Recombinant rat PAI1 protein (Biotin) is a Rat Full Length protein, in the 24 to 402 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, FuncS.
>95% SDS-PAGE
Escherichia coli
Tag free
SDS-PAGE, FuncS
Yes
ab170081 typically contains 50 percent active PAI1.
Biotin
P20961
No
Rat
pH: 5
Constituents: 2.34% Sodium chloride, 0.41% Sodium acetate, 0.03% EDTA
S P L P E S H T A Q Q A T N F G V K V F Q H V V Q A S K D R N V V F S P Y G V S S V L A M L Q L T T A G K T R Q Q I Q D A M G F N I S E R G T A P A L R K L S K E L M G S W N K N E I S T A D A I F V Q R D L E L V Q G F M P H F F K L F R T T V K Q V D F S E V E R A R F I I N D W V E R H T K G M I S D L L A K G A V N E L T R L V L V N A L Y F N G Q W K T P F L E A S T H Q R L F H K S D G S T I S V P M M A Q N N K F N Y T E F T T P D G H E Y D I L E L P Y H G E T L S M F I A A P F E K D V P L S A I T N I L D A E L I R Q W K S N M T R L P R L L I L P K F S L E T E V D L R G P L E K L G M T D I F S S T Q A D F T S L S D Q E Q L S V A Q A L Q K V K I E V N E S G T V A S S S T A I L V S A R M A P T E M V L D R S F L F V V R H N P T E T I L F M G Q L M E P
Full Length
43 kDa
24 to 402
Recombinant
Liquid
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
Belongs to the serpin family.
Dry Ice
-80°C
-80°C
Upon delivery aliquot
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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Terms & Conditions.
SDS-PAGE analysis of ab170081.
Lane 1: 3µg ab170081 Reduced
Lane 2: Rat PAI1 (3µg) + Urokinase (15µg) Reduced
Lane 3: Molecular weight markers
Avidin-Alkaline Phosphatase Western Blot analysis of ab170081.
Lane 1: 0.1µg ab170081 Reduced
Lane 2: Rat PAI1 (3µg) + Urokinase (2µg) Reduced
All lanes: Western blot - Recombinant rat PAI1 protein (Biotin) (ab170081)
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