Recombinant Rat RANTES protein is a Rat Full Length protein, in the 25 to 92 aa range, expressed in Escherichia coli, with >95% purity and < 1 EU/µg endotoxin level.
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Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Scya5, Ccl5, C-C motif chemokine 5, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES
Recombinant Rat RANTES protein is a Rat Full Length protein, in the 25 to 92 aa range, expressed in Escherichia coli, with >95% purity and < 1 EU/µg endotoxin level.
pH: 7.4
Constituents: 96% Phosphate Buffer, 2.922% Sodium chloride, 0.05845% EDTA
Affinity chromatography is used to purify
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Belongs to the intercrine beta (chemokine CC) family.
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