JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB109143

Recombinant Rat Visfatin protein

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Rat Visfatin protein is a Rat Full Length protein, in the 1 to 491 aa range, expressed in HEK 293 cells, with >90%, < 0.1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Pbef1, Nampt, Nicotinamide phosphoribosyltransferase, NAmPRTase, Pre-B-cell colony-enhancing factor 1 homolog, Visfatin, PBEF

Key facts

Purity

>90% SDS-PAGE

ab109143 is 0.2µm filtered

Endotoxin level

< 0.1 EU/µg

Expression system

HEK 293 cells

Tags

DDDDK tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q80Z29

Animal free

No

Carrier free

No

Species

Rat

Storage buffer

pH: 7.2 Constituents: PBS

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB256228

Recombinant Human Chemerin protein

SDS-PAGE - Recombinant Human Chemerin protein (AB256228)

  • 0
  • 0
Primary Antibodies

AB236874

Anti-Visfatin antibody [EPR21980]

RabMAb|Recombinant|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-Visfatin antibody [EPR21980] (AB236874)

  • 0
  • 0
Primary Antibodies

AB72965

Anti-Chemerin antibody

Immunocytochemistry/ Immunofluorescence - Anti-Chemerin antibody (AB72965)

  • 5
  • 1
Assay Kits

AB221819

NAMPT Activity Assay Kit (Colorimetric)

Functional Studies - NAMPT Activity Assay Kit (Colorimetric) (AB221819)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column

Product details

Working aliquots are stable for up to 3 months when stored at -20°C.
style
left-column

Sequence info

[{"linker":null,"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"60 kDa","actualMolecularWeight":null,"aminoAcidEnd":491,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q80Z29","tags":[{"tag":"DDDDK","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Form
Liquid
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

General info

Function

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component : CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Sequence similarities

Belongs to the NAPRTase family.

Subcellular localisation

Nucleus

style
left-column

Product protocols

style
left-column

Target data

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component : CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.
See full target information Nampt
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com