Anti-SV2A antibody [EPR23500-32] Blocking Peptide
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Anti-SV2A antibody [EPR23500-32] Blocking Peptide is a Synthetic blocking peptide. >90% and suitable for BL.
View Alternative Names
Kiaa0736, Sv2, Sv2a, Synaptic vesicle glycoprotein 2A, Synaptic vesicle protein 2, Synaptic vesicle protein 2A, Calcium regulator SV2A
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Specifications
Form
Lyophilized
General info
Function
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.. (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4 (PubMed : 16543415).. (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); BoNT/D does not bind to extracellular loop 4 as do BoNT/A and BoNT/E (PubMed : 21483489).. (Microbial infection) Receptor for C.botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4 (PubMed : 18815274). It probably requires glycosylation of Asn-573 (PubMed : 18815274).
Sequence similarities
Belongs to the major facilitator superfamily.
Post-translational modifications
Phosphorylation by CK1 of the N-terminal cytoplasmic domain regulates interaction with SYT1.. N-glycosylated.
Target data
Product promise
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