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AB315323

TRPC6 blocking peptide

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(0 Publication)

TRPC6 blocking peptide is a Synthetic peptide. >70%.

View Alternative Names

TRP6, TRPC6, Short transient receptor potential channel 6, TrpC6, Transient receptor protein 6, TRP-6

Key facts

Purity

>70%

Tags

Tag free

Biologically active

No

Accession

Q9Y210

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 0.1% BSA

storage-buffer

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Sequence info

[{"sequence":"","proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"Q9Y210","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
Up to 12 months
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Liquid

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General info

Function

Forms a receptor-activated non-selective calcium permeant cation channel (PubMed : 19936226, PubMed : 23291369, PubMed : 26892346, PubMed : 9930701). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed : 26892346). Seems not to be activated by intracellular calcium store depletion.

Sequence similarities

Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.

Post-translational modifications

Phosphorylated by FYN, leading to an increase of TRPC6 channel activity.

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Product protocols

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Target data

Forms a receptor-activated non-selective calcium permeant cation channel (PubMed : 19936226, PubMed : 23291369, PubMed : 26892346, PubMed : 9930701). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed : 26892346). Seems not to be activated by intracellular calcium store depletion.
See full target information TRPC6
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Complementary Products

Primary Antibodies

AB105845

Anti-TRPC6 antibody [3F2.H10.F2]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRPC6 antibody [3F2.H10.F2] (AB105845)

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