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AB286929

RNase R

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(11 Publications)

RNase R (Ribonuclease R) (ab286929) is an E. coli exoribonuclease that exhibits 3'-to-5' exonuclease activity, efficiently digesting nearly all linear RNA species.

- Efficiently digests linear RNA species with 3'-to-5' exonuclease activity
- High purity – contains RNase R at 10 U/µl for optimal performance
- Enriches for circular RNAs in biological samples

Key facts

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Product details

RNase R (ab286929, M1228-500) is an E. coli exoribonuclease which exhibits 3'-to-5' exonuclease activity, efficiently digesting nearly all linear RNA species.

This product is manufactured by BioVision, an Abcam company and was previously called M1228 RNase R. M1228-500 is the same size as the 1 kit size of ab286929.

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What's included?

{ "values": { "1Kit": { "sellingSize": "1 Kit", "publicAssetCode":"ab286929-1Kit", "assetComponentDetails": [ { "size":"1 x 1 mL", "name":"10X RNase R Reaction Buffer", "number":"AB286929-CMP01" }, { "size":"1 x 50 µL", "name":"RNase R (10 U/μl)", "number":"AB286929-CMP02" } ] }, "1Kit": { "sellingSize": "1 Kit", "publicAssetCode":"ab286929-1Kit", "assetComponentDetails": [ { "size":"1 x 1 mL", "name":"10X RNase R Reaction Buffer", "number":"AB286929-CMP01", "productcode":"" }, { "size":"1 x 50 µL", "name":"RNase R (10 U/μl)", "number":"AB286929-CMP02", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

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Publications (11)

Recent publications for all applications. Explore the full list and refine your search

Bio-protocol 15:e5310 PubMed40432763

2025

RNA PolyA Tailing Assay to Qualitatively Analyze Circular RNA Manufacturing.

Applications

Unspecified application

Species

Unspecified reactive species

Zih-Shiuan Chuang,Chan-I Su,Hsin-I Wang,Chia-Yi Yu

Hereditas 162:39 PubMed40087716

2025

CircCENPM serves as a CeRNA to aggravate nasopharyngeal carcinoma metastasis and stemness via enhancing BMI1.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Wang,Fei Wang

Molecular cancer 24:29 PubMed39856701

2025

Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Pan,Kailai Chen,Wei Gao,Meiqi Xu,Fanlong Meng,Mengyuan Wu,Zi Qi Wang,Yun Qi Li,Wanhai Xu,Manjie Zhang,Yakun Luo

Nature communications 15:6607 PubMed39098891

2024

A cis-acting ligase ribozyme generates circular RNA in vitro for ectopic protein functioning.

Applications

Unspecified application

Species

Unspecified reactive species

Chan-I Su,Zih-Shiuan Chuang,Chi-Ting Shie,Hsin-I Wang,Yu-Ting Kao,Chia-Yi Yu

PeerJ 12:e16967 PubMed38680890

2024

Circular RNA circMAN1A2 promotes ovarian cancer progression through the microRNA-135a-3p/IL1RAP/TAK1 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Li,Chuancui Hu,Da Zhao,Mingchao Nie,Xiaoli Wang

International journal of molecular sciences 25: PubMed38339175

2024

ADAMTS Gene-Derived circRNA Molecules in Non-Small-Cell Lung Cancer: Expression Profiling, Clinical Correlations and Survival Analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Jacek Pietrzak,Rafał Świechowski,Agnieszka Wosiak,Szymon Wcisło,Ewa Balcerczak

Animal cells and systems 27:208-218 PubMed37808549

2023

The RNA ligation method using modified splint DNAs significantly improves the efficiency of circular RNA synthesis.

Applications

Unspecified application

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Unspecified reactive species

Yoon-Seob Kim,Do-Hyung Kim,Daegi An,Younghyun Lim,Young-Jin Seo,Hak Kyun Kim,Ho-Young Kang

Oncology reports 50: PubMed37711054

2023

Circular RNA circBLNK promotes osteosarcoma progression and inhibits ferroptosis in osteosarcoma cells by sponging miR‑188‑3p and regulating GPX4 expression.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongjun Li,Yi Luo,Chunbo Wang,Dunxin Han,Weiping Sun

Alzheimer's & dementia : the journal of the Alzheimer's Association 19:3389-3405 PubMed36795937

2023

Identification of circRNAs linked to Alzheimer's disease and related dementias.

Applications

Unspecified application

Species

Unspecified reactive species

Sambhavi Puri,Junming Hu,Zhuorui Sun,Mintao Lin,Thor D Stein,Lindsay A Farrer,Benjamin Wolozin,Xiaoling Zhang

Journal of experimental & clinical cancer research : CR 41:261 PubMed36028854

2022

ALKBH5-mediated m6A modification of circCCDC134 facilitates cervical cancer metastasis by enhancing HIF1A transcription.

Applications

Unspecified application

Species

Unspecified reactive species

Leilei Liang,Yunshu Zhu,Jian Li,Jia Zeng,Lingying Wu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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