AB99909
Goat Anti-Human IgA (SureLight® PE)
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(1 Publication)
Suitable for Flow Cyt. Cited in 1 publication.
View Alternative Names
Immunoglobulin heavy constant alpha 1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, IGHA1
Reactivity data
{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "Flow Cyt": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/100 - 1/1000", "notes":"<p></p>" } } }
Properties and storage information
Form
Lyophilized
Reconstitution
reconstitute with water at 1mL
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.05% Sodium azide Constituents: 1.71% Sucrose, 1.64% Sodium phosphate, 0.58% Sodium chloride, 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Target data
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed : 2241915).
Additional targets
IGHA2
Publications (1)
Recent publications for all applications. Explore the full list and refine your search
The Journal of general virology 102: PubMed33961540
2021
Human convalescent plasma protects K18-hACE2 mice against severe respiratory disease.
Applications
Unspecified application
Species
Unspecified reactive species
Joseph W Golden,Xiankun Zeng,Curtis R Cline,Aura R Garrison,Lauren E White,Collin J Fitzpatrick,Steven A Kwilas,Philip A Bowling,Jimmy O Fiallos,Joshua L Moore,Willie B Sifford,Keersten M Ricks,Eric M Mucker,Jeffrey M Smith,Jay W Hooper
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