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BiochemicalsProteins and Peptides
Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Suitable for IHC-Fr, Flow Cyt, WB, ELISA. Preadsorbed to minimise non-specific binding and high background staining. Cited in 2 publications.
Goat
Human
IgG
F(ab')2
Mouse, Horse, Cow
Biotin
IHC-Fr, Flow Cyt, WB, ELISA
Polyclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application IHC-Fr | Reactivity Reacts | Dilution info 1/200.00000 - 1/1000.00000 | Notes - |
Application Flow Cyt | Reactivity Reacts | Dilution info 1/200.00000 - 1/1000.00000 | Notes - |
Application WB | Reactivity Reacts | Dilution info 1/1000.00000 - 1/10000.00000 | Notes - |
Application ELISA | Reactivity Reacts | Dilution info 1/1000.00000 - 1/10000.00000 | Notes - |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Suitable for IHC-Fr, Flow Cyt, WB, ELISA. Preadsorbed to minimise non-specific binding and high background staining. Cited in 2 publications.
Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Goat Anti-Human IgG (Fab')2 (Biotin) preadsorbed
Goat
Human
IgG
F(ab')2
Mouse, Horse, Cow
Biotin
IHC-Fr, Flow Cyt, WB, ELISA
Polyclonal
Yes
Native Full Length Protein corresponding to Human Immunoglobulin heavy constant gamma 1. Database link P01857
ab64666 is specific for Fab and F(ab')2 portion of human IgG by IEP. It reacts with other human immunoglobulins through common light chain reactivity.
No reactivity with the Fc portion of human IgG or non immunoglobulin serum proteins was detected.
IgG
Liquid
Preservative: 0.05% Sodium azide
Constituents: PBS
Affinity purification Immunogen
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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