AB97224

Goat Anti-Human IgG Fc (FITC)

Name: Goat Anti Human (IgG Fc) secondary antibody FITC (ab97224) | Abcam
Brand: Abcam Limited
SKU: AB97224
Price: 275 USD
Availability: InStock
Rating: 5 (1 reviews)

(1 Review)

(14 Publications)

Suitable for ICC/IF, IHC-P. Cited in 14 publications.

View Alternative Names

Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1

Unconjugated

Goat Anti-Human IgG Fc
Unconjugated

Goat Anti-Human IgG Fc preadsorbed
576 DyLight® 550

Goat Anti-Human IgG Fc (DyLight® 550) preadsorbed
673 DyLight® 650

Goat Anti-Human IgG Fc (DyLight® 650) preadsorbed
518 DyLight® 488

Goat Anti-Human IgG Fc (DyLight® 488)
Biotin

Goat Anti-Human IgG Fc (Biotin)
Alkaline Phosphatase

Goat Anti-Human IgG Fc (Alkaline Phosphatase)
SureLight® PE

Goat Anti-Human IgG Fc (SureLight® PE)
618 DyLight® 594

Goat Anti-Human IgG Fc (DyLight® 594) preadsorbed
HRP

Goat Anti-Human IgG Fc (HRP)

Key facts

Host species

Goat

Target species

Human

Target isotype

IgG

Target specificity

Fc region

Minimal cross-reactivity

Pre-adsorbed

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Applications

ICC/IF, IHC-P

applications

Clonality

Polyclonal

Isotype

IgG

Specificity

By immunoelectrophoresis and ELISA this antibody reacts specifically with Human IgG. Cross reactivity with other immunoglobulins and light chains is less than 0.1%.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ICC/IF": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/50 - 1/500", "notes":"<p></p>" }, "IHC-P": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/50 - 1/500", "notes":"<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Antiserum was solid phase adsorbed to ensure class specificity. This antibody was isolated by affinity chromatography using antigen coupled to agarose beads and conjugated to FITC.

Storage buffer

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: 99% PBS, 0.2% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

Visit the General protocols
Visit the Troubleshooting

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Target data

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus-infected cells.

See full target information IGHG1

Additional targets

IGHG2,IGHG3,IGHG4

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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed37298447

2023

Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Shih-Yao Chen,Chung-Teng Wang,Ching-Yi Chen,Pin-Yu Kuo,Chrong-Reen Wang,Ai-Li Shiau,Cheng-Hsi Chang,Chao-Liang Wu

Journal of cachexia, sarcopenia and muscle 14:1441-1453 PubMed37017344

2023

GDNF family receptor alpha-like antagonist antibody alleviates chemotherapy-induced cachexia in melanoma-bearing mice.

Applications

Unspecified application

Species

Unspecified reactive species

Beom Yong Lee,Jongwon Jeong,Inseong Jung,Hanchae Cho,Dokyung Jung,Jiwon Shin,Jun-Kook Park,Eunju Park,Soojeong Noh,Sanghee Shin,Sungmin Kang,Jong-Ik Heo,Moon-Chang Baek,Kyungmoo Yea

Plant biotechnology journal 20:2217-2230 PubMed35900183

2022

Impact of glycoengineering and antidrug antibodies on the anticancer activity of a plant-made lectin-Fc fusion protein.

Applications

Unspecified application

Species

Unspecified reactive species

Matthew Dent,Katarina L Mayer,Noel Verjan Garcia,Haixun Guo,Hiroyuki Kajiura,Kazuhito Fujiyama,Nobuyuki Matoba

Experimental dermatology 31:362-374 PubMed34694648

2021

Investigation of miR-126-3p loaded on adipose stem cell-derived exosomes for wound healing of full-thickness skin defects.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Ma,Zhaofeng Zhang,Yinmin Wang,Hua Shen

Scientific reports 11:19500 PubMed34593880

2021

A new humanized antibody is effective against pathogenic fungi in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Tomas Di Mambro,Tania Vanzolini,Pierpaolo Bruscolini,Sergio Perez-Gaviro,Emanuele Marra,Giuseppe Roscilli,Marzia Bianchi,Alessandra Fraternale,Giuditta Fiorella Schiavano,Barbara Canonico,Mauro Magnani

The journal of gene medicine 23:e3379 PubMed34296780

2021

Synovial mesenchymal stem cell-derived extracellular vesicles containing microRN555A-26a-5p ameliorate cartilage damage of osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Laiya Lu,Jingyi Wang,Aoyuan Fan,Pei Wang,Runzhi Chen,Laibing Lu,Feng Yin

Frontiers in immunology 12:701295 PubMed34394095

2021

Case Report: A Re-Positive Case of SARS-CoV-2 Associated With Glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoli Zhou,Ya-Na Zhou,Ashaq Ali,Cuiqin Liang,Zhiqin Ye,Xiaomin Chen,Qing Zhang,Lihua Deng,Xinyi Sun,Qian Zhang,Jihong Luo,Wei Li,Kun Zhou,Shanshan Cao,Xiaowei Zhang,Xiao-Dong Li,Xian-En Zhang,Zongqiang Cui,Dong Men

Vaccines 9: PubMed34066016

2021

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2.

Applications

Unspecified application

Species

Unspecified reactive species

Chotiwat Seephetdee,Nattawut Buasri,Kanit Bhukhai,Kitima Srisanga,Suwimon Manopwisedjaroen,Sarat Lertjintanakit,Nut Phueakphud,Chatbenja Pakiranay,Niwat Kangwanrangsan,Sirawat Srichatrapimuk,Suppachok Kirdlarp,Somnuek Sungkanuparph,Somchai Chutipongtanate,Arunee Thitithanyanont,Suradej Hongeng,Patompon Wongtrakoongate

Journal of microbiology (Seoul, Korea) 59:530-533 PubMed33907974

2021

Differences in seroprevalence between epicenter and non-epicenter areas of the COVID-19 outbreak in South Korea.

Applications

Unspecified application

Species

Unspecified reactive species

Hye Won Jeong,Hyun-Ha Chang,Eun Ji Kim,Yu Kyung Kim,Se-Mi Kim,Eun-Ha Kim,Young-Il Kim,Mark Anthony B Casel,Seong-Gyu Kim,Rare Rollon,Seung-Gyu Jang,Kwang-Min Yu,Hee-Sung Kim,Hee Sue Park,Su-Jin Park,Yong-Dae Kim,Eung-Gook Kim,Young Ki Choi

Experimental and therapeutic medicine 20:617-622 PubMed32509023

2020

Clinical features and outcomes of Chinese patients with anti-γ-aminobutyric acid B receptor encephalitis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiu-He Zhao,Xue Yang,Xue-Wu Liu,Sheng-Jun Wang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Goat Anti-Human IgG Fc (FITC)

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Key facts

Host species

Target species

Target isotype

Target specificity

Minimal cross-reactivity

Pre-adsorbed

Conjugation

Excitation/Emission

Applications

Clonality

Isotype

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Additional targets

Publications (14)

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Product promise