AB98616

Goat Anti-Human IgG Fc preadsorbed

Name: Goat Anti-Human IgG Fc preadsorbed secondary antibody (ab98616) | Abcam
Brand: Abcam Limited
SKU: AB98616
Price: 220 USD
Availability: InStock

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(6 Publications)

Suitable for ICC, ELISA, IHC-P, WB. Preadsorbed to minimise non-specific binding and high background staining. Cited in 6 publications.

View Alternative Names

Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1

Unconjugated

Goat Anti-Human IgG Fc
576 DyLight® 550

Goat Anti-Human IgG Fc (DyLight® 550) preadsorbed
673 DyLight® 650

Goat Anti-Human IgG Fc (DyLight® 650) preadsorbed
518 DyLight® 488

Goat Anti-Human IgG Fc (DyLight® 488)
Biotin

Goat Anti-Human IgG Fc (Biotin)
519 FITC

Goat Anti-Human IgG Fc (FITC)
Alkaline Phosphatase

Goat Anti-Human IgG Fc (Alkaline Phosphatase)
SureLight® PE

Goat Anti-Human IgG Fc (SureLight® PE)
618 DyLight® 594

Goat Anti-Human IgG Fc (DyLight® 594) preadsorbed
HRP

Goat Anti-Human IgG Fc (HRP)

Key facts

Host species

Goat

Target species

Human

Target isotype

IgG

Target specificity

Fc region

Minimal cross-reactivity

Mouse, Rat, Sheep, Rabbit, Goat, Horse, Chicken, Cow,

Pre-adsorbed

Yes

Applications

IHC-P, ELISA, WB, ICC

applications

Clonality

Polyclonal

Isotype

IgG

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ICC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/100 - 1/30000", "notes":"Coating: Use 1/100-1/500 dilution; Primary: Use 1/1,000-1/30,000 dilution." }, "IHC-P": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/200 - 1/2000", "notes":"" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/1000 - 1/30000", "notes":"Colorimetric: Use 1/1,000-1/10,000 dilution; Chemiluminescent: Use 1/1,000-1/30,000 dilution." } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

This antibody was isolated by affinity chromatography using antigen coupled to agarose beads.

Storage buffer

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

Visit the General protocols
Visit the Troubleshooting

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Target data

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus-infected cells.

See full target information IGHG1

Additional targets

IGHG4,IGHG2,IGHG3

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Methods in molecular biology (Clifton, N.J.) 2804:127-138 PubMed38753145

2024

Microfluidic Cartridge for Bead-Based Affinity Assays.

Applications

Unspecified application

Species

Unspecified reactive species

Inês F Pinto,Veronique Chotteau,Aman Russom

ACS sensors 6:842-851 PubMed33724791

2021

Multiplexed Microfluidic Cartridge for At-Line Protein Monitoring in Mammalian Cell Culture Processes for Biopharmaceutical Production.

Applications

Unspecified application

Species

Unspecified reactive species

Inês F Pinto,Ruben R G Soares,Meeri E-L Mäkinen,Veronique Chotteau,Aman Russom

Molecular cancer therapeutics 20:347-356 PubMed33293344

2020

Single-Dose Anti-PD-L1/IL-15 Fusion Protein KD033 Generates Synergistic Antitumor Immunity with Robust Tumor-Immune Gene Signatures and Memory Responses.

Applications

Unspecified application

Species

Unspecified reactive species

Stella A Martomo,Dan Lu,Zhanna Polonskaya,Xenia Luna,Zhikai Zhang,Sam Feldstein,Radovan Lumban-Tobing,Danielle K Almstead,Faical Miyara,Jeegar Patel

Journal of dairy science 103:5978-5991 PubMed32418693

2020

High-pressure homogenization and high hydrostatic pressure processing of human milk: Preservation of immunological components for human milk banks.

Applications

Unspecified application

Species

Unspecified reactive species

A Irazusta,C Rodríguez-Camejo,S Jorcin,A Puyol,L Fazio,F Arias,M Castro,A Hernández,T López-Pedemonte

Biotechnology and bioengineering 117:5-16 PubMed31631329

2019

Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERAD.

Applications

Unspecified application

Species

Unspecified reactive species

Sven Mathias,Anna Wippermann,Nadja Raab,Nikolas Zeh,René Handrick,Ingo Gorr,Patrick Schulz,Simon Fischer,Martin Gamer,Kerstin Otte

Journal of biotechnology 271:47-55 PubMed29477386

2018

Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy.

Applications

Species

Unspecified reactive species

Sven Mathias,Simon Fischer,René Handrick,Jürgen Fieder,Patrick Schulz,Harald Bradl,Ingo Gorr,Martin Gamer,Kerstin Otte

View all publications

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Product promise

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For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Goat Anti-Human IgG Fc preadsorbed

Related conjugates and formulations (10)

Key facts

Host species

Target species

Target isotype

Target specificity

Minimal cross-reactivity

Pre-adsorbed

Applications

Clonality

Isotype

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Additional targets

Publications (6)

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Product promise