Suitable for Flow Cyt, I-ELISA.
Goat
Human
IgG
Fd gamma
Flow Cyt, I-ELISA
Polyclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application Flow Cyt | Reactivity Reacts | Dilution info - | Notes - |
Application I-ELISA | Reactivity Reacts | Dilution info 1 µg/mL | Notes - |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus-infected cells.
, ,
Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Suitable for Flow Cyt, I-ELISA.
Goat Anti-Human IgG Fd gamma
Goat
Human
IgG
Fd gamma
Flow Cyt, I-ELISA
Polyclonal
No
Reacts with the Fd region of human IgG. Minimal reaction to the Fc region of Human IgG and other human immunoglobulins (IgM, IgD and IgA).
IgG
Liquid
pH: 8.2
Constituents: 100% Borate buffered saline
Affinity purification Immunogen
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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