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AB97231

Goat Anti-Mouse IgA alpha chain

5

(1 Review)

|

(9 Publications)

Suitable for ICC, WB, ELISA, IHC-P. Cited in 9 publications.

View Alternative Names

Ig alpha chain C region

Key facts

Host species

Goat

Target species

Mouse

Target isotype

IgA

Target specificity

Alpha chain

Minimal cross-reactivity
Pre-adsorbed

No

Applications

IHC-P, ICC, WB, ELISA

applications

Clonality

Polyclonal

Isotype

IgG

Specificity

By immunoelectrophoresis and ELISA this antibody reacts specifically with Mouse IgA. Cross reactivity with other immunoglobulins and light chains is less than 0.1%.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ICC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/1000 - 1/30000", "notes":"<p>Colorimetric: 1/1000 - 1/10000, Chemiluminescent: 1/1000 - 1/30000</p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/100 - 1/30000", "notes":"<p>Coating: 1/100 - 1/500, Primary: 1/1000 - 1/30000</p>" }, "IHC-P": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/200 - 1/2000", "notes":"<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Antiserum was solid phase adsorbed to ensure class specificity. This antibody was isolated by affinity chromatography using antigen coupled to agarose beads.
Storage buffer
pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

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Target data

Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
See full target information
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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 8:420 PubMed40075219

2025

Maternal high-fat diet disrupts intestinal mucus barrier of offspring by regulating gut immune receptor LRRC19.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Sun,Shumin Huang,Mengfan Li,Yunwei Yang,Jiahui Ma,Runxiang Xie,Jingyi Wang,Qianjing Zhao,Siqi Qin,Linlin He,Jiaying Jiang,Qing Zhao,Ge Jin,Xiang Liu,Huan Huang,Yazheng Yang,Jianmei Wei,Wentian Liu,Bangmao Wang,Rongcun Yang,Xiaomin Su,Hailong Cao

The Journal of experimental medicine 222: PubMed39969510

2025

PARP7 inhibits type I interferon signaling to prevent autoimmunity and lung disease.

Applications

Unspecified application

Species

Unspecified reactive species

Devon Jeltema,Kennady Knox,Nicole Dobbs,Zhen Tang,Cong Xing,Antonina Araskiewicz,Kun Yang,Ivan Rodriguez Siordia,Jason Matthews,Michael Cohen,Nan Yan

iScience 27:110350 PubMed39108722

2024

Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology.

Applications

Unspecified application

Species

Unspecified reactive species

Lu Zhang,Yan He,Mengqin Zhang,Jimin Zhang,Wuwei Zhuang,Yuechi Sun,Xing Chen,Hangzhou Fu,Xuanli Tang,Guixiu Shi

Life (Basel, Switzerland) 13: PubMed37763339

2023

Secretory IgA-ETEC F5 Immune Complexes Promote Dendritic Cell Differentiation and Prime T Cell Proliferation in the Mouse Intestine.

Applications

Unspecified application

Species

Unspecified reactive species

Da Qin,Ying Li,Xiaoyan Chen,Liyang Li,Guihua Wang,Xilin Hou,Liyun Yu

Vaccines 11: PubMed37112742

2023

Early Oral Administration of Ginseng Stem-Leaf Saponins Enhances the Peyer's Patch-Dependent Maternal IgA Antibody Response to a PEDV Inactivated Vaccine in Mice, with Gut Microbiota Involvement.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Su,Junxing Li,Yin Xue,Bin Yu,Shiyi Ye,Lihua Xu,Yuan Fu,Xiufang Yuan

Foods (Basel, Switzerland) 11: PubMed35563952

2022

Stimulates Intestinal Secretion of Immunoglobulin A in an Individual-Specific Manner.

Applications

Unspecified application

Species

Unspecified reactive species

Liya Mei,Ying Chen,Jialiang Wang,Jian Lu,Jianxin Zhao,Hao Zhang,Gang Wang,Wei Chen

Histology and histopathology 37:655-664 PubMed35297032

2022

Class II lupus nephritis with podocyte injury in imiquimod-induced lupus-prone mice.

Applications

Unspecified application

Species

Unspecified reactive species

Atsuko Murai,Masaki Yamazaki,Kaori Nishihara,Aki Kito,Sohei Oyama,Naoshi Horiba,Atsuhiko Kato

Lupus science & medicine 8: PubMed34836923

2021

Prevention and partial reversion of the lupus phenotype in ABIN1[D485N] mice by an IRAK4 inhibitor.

Applications

Unspecified application

Species

Unspecified reactive species

Tsvetana Petrova,Sambit K Nanda,Cheryl Scudamore,Stephen W Wright,Vikram R Rao,Philip Cohen

Immunity 48:120-132.e8 PubMed29343433

2018

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Johanna Emgård,Hana Kammoun,Bethania García-Cassani,Julie Chesné,Sara M Parigi,Jean-Marie Jacob,Hung-Wei Cheng,Elza Evren,Srustidhar Das,Paulo Czarnewski,Natalie Sleiers,Felipe Melo-Gonzalez,Egle Kvedaraite,Mattias Svensson,Elke Scandella,Matthew R Hepworth,Samuel Huber,Burkhard Ludewig,Lucie Peduto,Eduardo J Villablanca,Henrique Veiga-Fernandes,João P Pereira,Richard A Flavell,Tim Willinger
View all publications
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