Suitable for Dot, ELISA, WB, ICC/IF.
Mouse
Human
IgG4
Fc region
FITC
Ex: 495nm, Em: 519nm
Dot, ELISA, WB, ICC/IF
Monoclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application Dot | Reactivity Reacts | Dilution info - | Notes (for Dot and slot immunoblotting) |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Application ICC/IF | Reactivity Reacts | Dilution info 1 µg for 106 Cells | Notes - |
Select an associated product type
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Immunoglobulin heavy constant gamma 4, Ig gamma-4 chain C region, IGHG4
Suitable for Dot, ELISA, WB, ICC/IF.
Anti-Human IgG4 pFc’ [HP6023] (FITC)
Mouse
Human
IgG4
Fc region
FITC
Ex: 495nm, Em: 519nm
Dot, ELISA, WB, ICC/IF
Monoclonal
HP6023
No
ab99815 reacts with the pFc’ portion of the heavy chain of Human IgG4.
IgG3
kappa
Liquid
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS
Affinity purification Protein A
Blue Ice
+4°C
+4°C
Store in the dark
Source: Ascites fluid
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