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AB99779

Mouse monoclonal [31-7-4] Anti-Human IgG2 Fc (HRP)

5

(1 Review)

|

(8 Publications)

Suitable for Dot, WB, ICC, IHC-Fr, ELISA. Ideal for western blot. Cited in 8 publications.

View Alternative Names

Immunoglobulin heavy constant gamma 2, Ig gamma-2 chain C region, Ig gamma-2 chain C region DOT, Ig gamma-2 chain C region TIL, Ig gamma-2 chain C region ZIE, IGHG2

1 Images
ELISA - Mouse monoclonal [31-7-4] Anti-Human IgG2 Fc (HRP) (AB99779)
  • ELISA

Supplier Data

ELISA - Mouse monoclonal [31-7-4] Anti-Human IgG2 Fc (HRP) (AB99779)

ELISA plate was coated with purified human IgG1, IgG2, IgG3, and IgG4. Immunoglobulins were detected with serially diluted ab99779.

Key facts

Host species

Mouse

Target species

Human

Target isotype

IgG2

Target specificity

Fc region

Minimal cross-reactivity
Pre-adsorbed

No

Conjugation

HRP

Excitation/Emission
Applications

ELISA, ICC, IHC-Fr, Dot, WB

applications

Clonality

Monoclonal

Clone number

31-7-4

Isotype

IgG1

Light chain type

kappa

Immunogen

Full Length Protein corresponding to Human IGHG2. The exact immunogen used to generate this antibody is proprietary information.

P01859

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "Dot": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ICC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "IHC-Fr": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1/1000 - 1/2000", "notes":"<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Product protocols

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Target data

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268).
See full target information IGHG2
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Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 19:55 PubMed37386541

2023

No impact of helminth coinfection in patients with smear positive tuberculosis on immunoglobulin levels using a novel method measuring Mycobacterium tuberculosis-specific antibodies.

Applications

Unspecified application

Species

Unspecified reactive species

Giggil Pushpamithran,Camilla Skoglund,Fanny Olsson,Melissa Méndez-Aranda,Thomas Schön,Mårten Segelmark,Olle Stendahl,Robert H Gilman,Robert Blomgran

Frontiers in immunology 12:767981 PubMed34804055

2021

SARS-CoV-2 Antibodies Mediate Complement and Cellular Driven Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Ida Jarlhelt,Sif Kaas Nielsen,Camilla Xenia Holtermann Jahn,Cecilie Bo Hansen,Laura Pérez-Alós,Anne Rosbjerg,Rafael Bayarri-Olmos,Mikkel-Ole Skjoedt,Peter Garred

Viruses 12: PubMed33138336

2020

Association of Genetic Polymorphisms in , , , and with the Clinical Forms of Dengue in Patients from Veracruz, Mexico.

Applications

Unspecified application

Species

Unspecified reactive species

Araceli Posadas-Mondragón,José Leopoldo Aguilar-Faisal,Gerardo Zuñiga,Jonathan Javier Magaña,José Angel Santiago-Cruz,Edith Guillén-Salomón,Verónica Alcántara-Farfán,María Luisa Arellano-Flores,Juan Santiago Salas-Benito,Rocío M Neri-Bazán,Lucero Luna-Rojas,Amanda Marineth Avila-Trejo,Adolfo Chávez-Negrete

PLoS pathogens 16:e1008796 PubMed32913364

2020

A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients.

Applications

Unspecified application

Species

Unspecified reactive species

Yuxin Chen,Xin Tong,Yang Li,Bin Gu,Jiawei Yan,Yong Liu,Han Shen,Rui Huang,Chao Wu

Arteriosclerosis, thrombosis, and vascular biology 39:1884-1892 PubMed31315438

2019

Association Between ApoA-I (Apolipoprotein A-I) Immune Complexes and Adverse Cardiovascular Events-Brief Report.

Applications

Unspecified application

Species

Unspecified reactive species

David Henson,Ayman Samman Tahhan,David Nardo,Arshed Ali Quyyumi,Vincent J Venditto

The Journal of allergy and clinical immunology 143:736-745.e6 PubMed29852256

2018

Identification of galectin-3 as an autoantigen in patients with IgG-related disease.

Applications

ELISA

Species

Unspecified reactive species

Cory A Perugino,Sultan B AlSalem,Hamid Mattoo,Emanuel Della-Torre,Vinay Mahajan,Gayathri Ganesh,Hugues Allard-Chamard,Zachary Wallace,Sydney B Montesi,Johannes Kreuzer,Wilhelm Haas,John H Stone,Shiv Pillai

The Journal of allergy and clinical immunology 141:2289-2292.e7 PubMed29421273

2018

Characterization of drug-neutralizing antibodies in patients with Fabry disease during infusion.

Applications

Unspecified application

Species

Unspecified reactive species

Malte Lenders,Boris Schmitz,Stefan-Martin Brand,Dirk Foell,Eva Brand

Microbiology and immunology 61:433-441 PubMed28881485

2017

Indices of anti-dengue immunoglobulin G subclasses in adult Mexican patients with febrile and hemorrhagic dengue in the acute phase.

Applications

Unspecified application

Species

Unspecified reactive species

Araceli Posadas-Mondragón,José Leopoldo Aguilar-Faisal,Adolfo Chávez-Negrete,Edith Guillén-Salomón,Verónica Alcántara-Farfán,Lucero Luna-Rojas,Amanda Marineth Ávila-Trejo,Judith Del Carmen Pacheco-Yépez
View all publications
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