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BiochemicalsProteins and Peptides
Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Suitable for Dot, ELISA, WB, IHC-Fr, ICC/IF.
Mouse
Human
IgA1
Fc region
PE
Ex: 480;565nm, Em: 578nm
Dot, ELISA, WB, IHC-Fr, ICC/IF
Monoclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application Dot | Reactivity Reacts | Dilution info - | Notes for Dot and slot immunoblotting |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Application IHC-Fr | Reactivity Reacts | Dilution info - | Notes - |
Application ICC/IF | Reactivity Reacts | Dilution info 0.2 µg for 106 Cells | Notes - |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
Immunoglobulin heavy constant alpha 1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, IGHA1
Suitable for Dot, ELISA, WB, IHC-Fr, ICC/IF.
Immunoglobulin heavy constant alpha 1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, IGHA1
Mouse monoclonal [B3506B4] Anti-Human IgA1 Fc (PE)
Mouse
Human
IgA1
Fc region
PE
Ex: 480;565nm, Em: 578nm
Dot, ELISA, WB, IHC-Fr, ICC/IF
Monoclonal
B3506B4
No
ab99797 reacts with the Fc portion of the heavy chain of IgA1.
IgG1
kappa
Liquid
pH: 7.3
Preservative: 0.1% Sodium azide
Constituents: PBS, Sucrose
Affinity purification Protein G
Blue Ice
+4°C
Store in the dark
Source: Ascites fluid
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