Suitable for IHC-Fr, ELISA, IM, Flow Cyt, ICC/IF. Cited in 2 publications.
Rabbit
Human
IgG
Heavy & Light chains
FITC
Ex: 495nm, Em: 519nm
IHC-Fr, ELISA, IM, Flow Cyt, ICC/IF
Polyclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application IHC-Fr | Reactivity Expected | Dilution info - | Notes - |
Application ELISA | Reactivity Expected | Dilution info 1/10000 - 1/50000 | Notes - |
Application IM | Reactivity Expected | Dilution info 1/1000 - 1/5000 | Notes - |
Application Flow Cyt | Reactivity Expected | Dilution info 1/500 - 1/2500 | Notes - |
Application ICC/IF | Reactivity Expected | Dilution info 1/1000 - 1/5000 | Notes - |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus-infected cells.
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Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Suitable for IHC-Fr, ELISA, IM, Flow Cyt, ICC/IF. Cited in 2 publications.
Rabbit Anti-Human IgG H&L (FITC)
Rabbit
Human
IgG
Heavy & Light chains
FITC
Ex: 495nm, Em: 519nm
IHC-Fr, ELISA, IM, Flow Cyt, ICC/IF
Polyclonal
No
Liquid
pH: 6.5
Preservative: 0.01% Sodium azide
Constituents: 1% BSA, 0.878% Sodium chloride, 0.424% Tripotassium orthophosphate
Affinity purification
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Human IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities.
Blue Ice
+4°C
+4°C
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