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14-3-3 protein theta

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity).

Sequence Similarities

Belongs to the 14-3-3 family.

Cellular localization

Alternative names

14-3-3 protein theta, 14-3-3 protein tau, Ywhaq

swissprot:P68254 entrezGene:100503129 entrezGene:22630