2SS_SOYBN
Developmental stage
Expressed from 3 weeks after flowering until the early desiccation stage, 7 weeks after flowering. Not detected in mature seeds. This temporal expression coincides with the initiation of mitotic arrest and DNA endoreduplication in developing soybean cotyledon.
Domain
2S albumin small chain
The poly-Asp C-terminal domain (56-64) of the small chain is necessary for its histone binding and antimitotic effect.
Function
This is a 2S seed storage protein.
2S albumin small chain
Binds to mammalian chromatin, preventing the normal formation of the kinetochore complex in the centromere and leading to the disruption of mitosis (PubMed:10331812).
Sequence Similarities
Belongs to the 2S seed storage albumins family.
Tissue Specificity
Expressed in cotyledons (Ref.2). Maximal expression in parenchyma cells undergoing DNA endoreduplication and cell expansion but not in actively dividing cells of the cotyledon (PubMed:10331812).
Alternative names
2S seed storage albumin protein, 2S albumin, GM2S-1, Napin-type 2S albumin 3