9b
Function
Plays a role in inhibiting the host innate immune response by targeting the mitochondrial-associated innate immune response. Acts by binding to host TOMM70, inhibiting its binding to HSP90AB1 thereby disrupting the interferon activation pathway.
Sequence Similarities
Belongs to the coronavirus group 2 protein 9b family.
Cellular localization
- Host cytoplasm
- Host mitochondrion
Alternative names
ORF9b protein, ORF9b, Accessory protein 9b, ORF-9b, Protein 9b, 9b