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ABHD17C

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS and DLG4/PSD95.

Post-translational modifications

Palmitoylated on cysteine residues located in a cysteine cluster at the N-terminus which promotes membrane localization. Palmitoylation is required for post-synaptic localization and for depalmitoylating activity towards DLG4/PSD95.

Sequence Similarities

Belongs to the AB hydrolase superfamily. ABHD17 family.

Cellular localization

Alternative names

FAM108C1, ABHD17C, Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C

swissprot:Q6PCB6 entrezGene:58489