ABI3
Function
May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.
Sequence Similarities
Belongs to the ABI family.
Tissue Specificity
Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
Cellular localization
- Cytoplasm
- Colocalizes with PAK2 at leading edge of cells.
Alternative names
NESH, ABI3, ABI gene family member 3, New molecule including SH3, Nesh