Ache

Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.

Belongs to the type-B carboxylesterase/lipase family.

Isoform H is highly expressed in erythrocytes.

• Synapse
• Secreted
• Cell membrane
• Peripheral membrane protein
• Isoform T
• Nucleus
• Only observed in apoptotic nuclei.
• Isoform H
• Cell membrane
• Lipid-anchor
• GPI-anchor
• Extracellular side

Acetylcholinesterase, AChE, ACHE

• entrezGene:43
• omim:100740
• swissprot:P22303

Proteins

Neuroscience

• Cardiovascular

67796Da