Ache

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

Belongs to the type-B carboxylesterase/lipase family.

Predominates in most expressing tissues except erythrocytes where a glycophospholipid-attached form of ACHE predominates.

• Synapse
• Secreted
• Cell membrane
• Peripheral membrane protein
• Isoform H
• Cell membrane
• Lipid-anchor
• GPI-anchor
• Extracellular side

Acetylcholinesterase, AChE, Ache

• entrezGene:11423
• swissprot:P21836

Proteins

Neuroscience

• Cardiovascular

68169Da