ACOT1
Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).
Pathway
Lipid metabolism; fatty acid metabolism.
Sequence Similarities
Belongs to the C/M/P thioester hydrolase family.
Cellular localization
- Cytoplasm
- Cytosol
Alternative names
CTE1, ACOT1, Acyl-coenzyme A thioesterase 1, Acyl-CoA thioesterase 1, CTE-I, CTE-Ib, Inducible cytosolic acyl-coenzyme A thioester hydrolase, Long chain acyl-CoA thioester hydrolase, Palmitoyl-coenzyme A thioesterase, Long chain acyl-CoA hydrolase