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ACTN3

Function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Sequence Similarities

Belongs to the alpha-actinin family.

Tissue Specificity

Expression restricted to fast (type 2) skeletal muscle fibers (at protein level).

Alternative names

Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3

swissprot:Q08043 entrezGene:89 omim:102574