Actr3b
Function
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors (By similarity).
Sequence Similarities
Belongs to the actin family. ARP3 subfamily.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cell projection
Alternative names
Actin-related protein 3B, ARP3-beta, Actin-like protein 3B, Actr3b