Acyl-CoA-binding protein
Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Sequence Similarities
Belongs to the ACBP family.
Cellular localization
- Endoplasmic reticulum
- Golgi apparatus
- Golgi localization is dependent on ligand binding.
Alternative names
Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, Endozepine, DBI, EP, Dbi